Cervical Preparation of Abortions Under Paracervical Block in the First Trimester:

Completed 110 enrolled Assistance Publique Hopitaux De Marseille

RandomizedParallel-groupSingle-blindTreatment

Summary

Surgical abortion is one of the most frequently surgery of women in the world. 43 millions are annually performed in the world. 90% of the abortions are performed during the first trimester of pregnancy before 13 weeks. Legal surgical abortion during the first trimester of pregnancy is a low risk intervention with a mortality rate lower than 1/100 000 abortions, with a risk of complications from 0.3 % to 3.4 %.

Timeline

Start: 2017-06-01
Primary completion: 2019-03-13
Completion: 2022-11-15

Publications

Hamdaoui N, Cardinale C, Fabre C, Baumstarck K, Agostini A. Pain Associated With Cervical Priming for First-Trimester Surgical Abortion: A Randomized Controlled Trial. Obstet Gynecol. 2021 Jun 1;137(6):1055-1060. doi: 10.1097/AOG.0000000000004376.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Mifepristone	Small molecule	200 mg	Oral
Subject	Misoprostol	Other / unclassified	0.4 mg	Other

Indications

No indication recorded.