Mifepristone

also known as RU-486 · Corlux · Mifegyne · Korlym · Mifeprex · VGX-410 · C-1073 · Medicane · +4 more

Developed for: major depressive disorder · post-traumatic stress disorder · pregnancy disorder · pregnancy disorder with abortive outcome · psychotic disorder · breast cancer · Cushing syndrome · leiomyoma
+50 more
· menstrual disorder · persian gulf syndrome · uterine benign neoplasm · adenomyosis · anxiety disorder · Cushing disease due to pituitary adenoma · depressive disorder · female breast carcinoma · male breast carcinoma · malignant epithelial tumor of ovary · non-small cell lung carcinoma · primary peritoneal carcinoma · type 2 diabetes mellitus · adrenal gland hyperfunction · Alzheimer disease · bipolar disorder · borderline personality disorder · cancer · central serous chorioretinopathy · diabetes mellitus · ductal breast carcinoma in situ · ectopic Cushing syndrome · endometrial cancer · endometriosis · fallopian tube cancer · fallopian tube carcinoma · hereditary breast ovarian cancer syndrome · HIV infectious disease · hormone-resistant prostate carcinoma · invasive breast carcinoma · meningioma · occupational disorder · ovarian cancer · pregnancy loss, recurrent, 4 · preterm premature rupture of the membranes · prostate adenocarcinoma · prostate cancer · sarcoma · submucous uterine fibroid · transitional cell carcinoma · triple-negative breast carcinoma · vaginal disorder · alcohol abuse · alcohol dependence · alcohol-related disorders · benign neoplasm of corpus uteri · bipolar depression · cocaine dependence · habitual spontaneous abortion · nicotine dependence
Investigated by: Gynuity Health Projects · Corcept Therapeutics · Stanford University · Boston University · Society of Family Planning · University of Chicago
+133 more
· Mediterranea Medica S. L. · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Karolinska Institutet · National Cancer Institute (NCI) · University of Pittsburgh · Washington University School of Medicine · Assistance Publique Hopitaux De Marseille · Cuidado Integral de la Mujer, Gineclinic, S.C. · HRA Pharma · Jiaxing Maternity and Child Health Care Hospital · Massachusetts General Hospital · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Nova Southeastern University · Santa Clara Valley Medical Center · University of California, Davis · University of California, San Diego · University of California, San Francisco · Women's Hospital School Of Medicine Zhejiang University · Amsterdam UMC, location VUmc · Anhui Province Cancer Hospital · Anhui Provincial Hospital · Antonia New · Assistance Publique - Hôpitaux de Paris · Astellas Pharma US, Inc. · Beth Israel Deaconess Medical Center · Bharatpur Eye Hospital · BioPro Medical Ltd · Breast Cancer Research Foundation · Brigham and Women's Hospital · Bronx Veterans Medical Research Foundation, Inc · CREHPA · Canisius-Wilhelmina Hospital · Center for Information and Counseling on Reproductive Health - Tanadgoma · Center for Research on Environment, Health and Population Activities · Centre de Formation et de la Recherche, Tunisia · Charitable Foundation Women Health & Family Planning · Charles Drew University of Medicine and Science · Check, Jerome H., M.D., Ph.D. · Chelsea and Westminster NHS Foundation Trust · Children's Investment Fund Foundation · China Resources Zizhu Pharmaceutical Co., Ltd. · Christiaan Vinkers · Clinical Hospital Merkur · Dana-Farber Cancer Institute · Daniel Grossman · Daniel Grossman, MD · Dartmouth-Hitchcock Medical Center · Eli Lilly and Company · First Affiliated Hospital of Wenzhou Medical University · Georgetown University · Grand Challenges Canada · Gynecologic Oncology Group · HaEmek Medical Center, Israel · Hadassah Medical Organization · Healthy Life · Hopital La Rabta · Hospital Provincial Magdalena V. de Martínez · Huzhou Maternity and Child Care Hospital · Ibis Reproductive Health · Icahn School of Medicine at Mount Sinai · Indiana University · Innovatiefonds Zorgverzekeraars · Institute for the Study of Aging (ISOA) · Instituto de Biología y Medicina Experimental (IBYME-CONICET) · James J. Peters Veterans Affairs Medical Center · Jinhua Municipal Central Hospital · Johns Hopkins University · KIST Medical College · KIST Medical College and Teaching Hospital · Kaiser Permanente · Kathmandu Medical College and Teaching Hospital · Kathmandu Model Hospital · Leiden University Medical Center · Lumbini Provincial Hospital · all 139 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Label expansion	US (FDA)	MIFEPREX	—	2016-03-29	fda.gov ↗
Approved	US (FDA)	MIFEPREX	—	2000-09-28	fda.gov ↗

Trials 141 · started per year

today

US approved 2000

1992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT06616077	Jun 2022 → Apr 2023	endometrial disorder, progesterone resistance	Reproductive Health Research Insritute, Chile	Completed	No outcome recorded
Phase 0	NCT05151016	Dec 2021 → Dec 2023	adenomyosis	Women's Hospital School Of Medicine Zhejiang University	Unknown	No outcome recorded
Phase 0	NCT01138553	Jun 2010 → Jun 2014	ductal breast carcinoma in situ, invasive breast carcinoma	University of California, San Diego	Terminated	No outcome recorded
Phase 115 trials
Phase 1	NCT06502158	Oct 2024 → Oct 2026 expected	—	Montefiore Medical Center	Recruiting	No outcome recorded
Phase 1	NCT04254627	Sep 2021 → Sep 2025	persian gulf syndrome	Nova Southeastern University	Completed	No outcome recorded
Phase 1	NCT04255498	Oct 2017 → Aug 2019	occupational disorder, persian gulf syndrome	South Florida Veterans Affairs Foundation for Research and Education	Unknown	No outcome recorded
Phase 1	NCT03258372	Aug → Nov 2017	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT03259542	Aug → Dec 2017	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT03508635	Sep 2014 → Dec 2015	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT02099825	Jan 2014 → Oct 2022	anxiety disorder	Washington University School of Medicine	Terminated	No outcome recorded
Phase 1	NCT02014337	Jan 2014 → Dec 2017	breast cancer, malignant epithelial tumor of ovary, non-small cell lung carcinoma, prostate cancer +2	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT02046421	Nov 2013 → May 2018	fallopian tube carcinoma, male breast carcinoma, malignant epithelial tumor of ovary, primary peritoneal carcinoma	University of Chicago	Completed	No outcome recorded
Phase 1	NCT01988610	Oct 2013 → Feb 2017	depressive disorder	Stanford University	Completed	No outcome recorded
Phase 1	NCT01493310	Nov 2011 → May 2018	female breast carcinoma, male breast carcinoma	University of Chicago	Completed	No outcome recorded
Phase 1	NCT00698022	Nov 2008 → Feb 2009	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT00752843	Sep → Nov 2008	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 1	NCT00592215	Mar 2008 → Apr 2010	—	Johns Hopkins University	Withdrawn	No outcome recorded
Phase 1	NCT00554177	Sep 2007 → Sep 2008	post-traumatic stress disorder	Antonia New	Completed	No outcome recorded

Phase 1/25 trials
Phase 1/2	NCT02012296	Dec 2013 → Jun 2019	hormone-resistant prostate carcinoma	University of Chicago	Completed	No outcome recorded
Phase 1/2	NCT01333098	Sep 2012 → Apr 2013	anxiety disorder	Washington University School of Medicine	Completed	No outcome recorded
Phase 1/2	NCT01419535	Nov 2011 → Nov 2015	diabetes mellitus	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Completed	No outcome recorded
Phase 1/2	NCT00721201	Nov 2008 → Mar 2010	Cushing syndrome	Sheffield Teaching Hospitals NHS Foundation Trust	Completed	No outcome recorded
Phase 1/2	NCT00099645	? → Aug 2005	HIV infectious disease	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 229 trials
Phase 2	NCT06689254	Nov 2024 → Sep 2026 expected	post-traumatic stress disorder	Christiaan Vinkers	Recruiting	No outcome recorded
Phase 2	NCT06099769	Oct 2023 → Oct 2027 expected	breast cancer	Memorial Sloan Kettering Cancer Center	Recruiting	No outcome recorded
Phase 2	NCT05177510	Aug 2023 → Dec 2026 expected	—	Chelsea and Westminster NHS Foundation Trust	Recruiting	No outcome recorded
Phase 2	NCT05217758	Dec 2021 → Aug 2024	major depressive disorder	Amsterdam UMC, location VUmc	Completed	No outcome recorded
Phase 2	NCT04588688	May → Aug 2021	secondary adrenal insufficiency	Tobias Else	Terminated	No outcome recorded
Phase 2	NCT04676776	Jan → Dec 2021	—	Gynuity Health Projects	Unknown	No outcome recorded
Phase 2	NCT03972358	Feb 2020 → Dec 2021	menstrual disorder	Gynuity Health Projects	Unknown	No outcome recorded
Phase 2	NCT03714880	Apr 2019 → Feb 2021	—	University of California, Davis	Terminated	No outcome recorded
Phase 2	NCT03225547	Feb 2018 → Sep 2025	triple-negative breast carcinoma	University of Chicago	Terminated	No outcome recorded
Phase 2	NCT02788981	Mar 2017 → Dec 2022 overdue	breast cancer	University of Chicago	Active not recruiting	No outcome recorded
Phase 2	NCT03052400	Feb 2017 → Mar 2021	type 2 diabetes mellitus	Charles Drew University of Medicine and Science	Terminated	No outcome recorded
Phase 2	NCT02642939	Dec 2015 → Oct 2020	non-small cell lung carcinoma	Check, Jerome H., M.D., Ph.D.	Terminated	No outcome recorded
Phase 2	NCT02354170	Jan 2015 → Apr 2017	central serous chorioretinopathy	Roger Goldberg, M.D., MBA	Completed	No outcome recorded
Phase 2	NCT01898312	Sep 2013 → Dec 2021	hereditary breast ovarian cancer syndrome	Karolinska Institutet	Completed	No outcome recorded
Phase 2	NCT01931657	Aug 2013 → Dec 2015	—	Karolinska Institutet	Completed	No outcome recorded
Phase 2	NCT01739335	Nov 2012 → Sep 2016	post-traumatic stress disorder	VA Office of Research and Development	Completed	No outcome recorded
Phase 2	NCT01294319	Jan 2011 → Aug 2016	glucocorticoid resistance	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	No outcome recorded
Phase 2	NCT01212588	Sep 2010 → Sep 2016	borderline personality disorder	Indiana University	Terminated	No outcome recorded
Phase 2	NCT00881140	Apr 2009 → May 2012	uterine benign neoplasm, vaginal disorder	BioPro Medical Ltd	Completed	No outcome recorded
Phase 2	NCT00833339	May 2008 → Oct 2015	post-traumatic stress disorder	James J. Peters Veterans Affairs Medical Center	Unknown	No outcome recorded
Phase 2	NCT00422201	May 2007 → Apr 2012	ectopic Cushing syndrome	HRA Pharma	Terminated	No outcome recorded
Phase 2	NCT00459290	May 2007 → Jul 2010	fallopian tube cancer, ovarian cancer, primary peritoneal carcinoma	Gynecologic Oncology Group	Completed	No outcome recorded
Phase 2	NCT00455442	Mar → Jul 2007	—	Corcept Therapeutics	Completed	No outcome recorded
Phase 2	NCT00330993	Mar → Aug 2006	—	University of Pittsburgh	Completed	No outcome recorded
Phase 2	NCT00140478	Feb 2005 → Jun 2006	prostate adenocarcinoma	Dana-Farber Cancer Institute	Completed	No outcome recorded
Phase 2	NCT00219778	Dec 2004 → Feb 2010	leiomyoma	Poitiers University Hospital	Terminated	No outcome recorded
Phase 2	NCT00105105	Apr 2003 → Nov 2005	Alzheimer disease	Corcept Therapeutics	Terminated	No outcome recorded
Phase 2	NCT00043654	Aug 2002 → Jun 2007	bipolar disorder	National Institute of Mental Health (NIMH)	Completed	No outcome recorded
Phase 2	NCT00505739	Sep 2001 → Oct 2007	endometrial cancer	M.D. Anderson Cancer Center	Completed	No outcome recorded

Phase 2/37 trials
Phase 2/3	NCT06492889	Jul 2024 → Jun 2025 overdue	pregnancy disorder	Gynuity Health Projects	Not yet recruiting	No outcome recorded
Phase 2/3	NCT03520439	May 2018 → Jul 2019	adenomyosis	xinmei zhang	Completed	No outcome recorded
Phase 2/3	NCT02271958	Nov 2010 → Oct 2013	endometriosis	Mediterranea Medica S. L.	Completed	No outcome recorded
Phase 2/3	NCT01786226	Mar 2010 → Mar 2012	uterine benign neoplasm	Mediterranea Medica S. L.	Terminated	No outcome recorded
Phase 2/3	NCT00886873	May 2008 → Apr 2009	uterine benign neoplasm	Mediterranea Medica S. L.	Completed	No outcome recorded
Phase 2/3	NCT00712595	Jan 2007	leiomyoma	Mediterranea Medica S. L.	Completed	No outcome recorded
Phase 2/3	NCT00725270	Apr 1998 → May 2009	major depressive disorder, psychotic disorder	Stanford University	Terminated	No outcome recorded
Phase 321 trials
Phase 3	NCT07506512	Jul 2026 → Jul 2031 expected	pregnancy loss, recurrent, 4	University of Pennsylvania	Not yet recruiting	No outcome recorded
Phase 3	NCT06394999	May 2025 → Jun 2027 expected	—	Leiden University Medical Center	Active not recruiting	No outcome recorded
Phase 3	NCT05016349	Aug → Oct 2021	female breast carcinoma	Mahmoud Ramadan mohamed Elkazzaz	Unknown	No outcome recorded
Phase 3	NCT03269279	May 2017 → Dec 2019	—	Gynuity Health Projects	Unknown	No outcome recorded
Phase 3	NCT02985229	Oct 2016 → Jul 2017	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 3	NCT01925092	Aug 2013 → Dec 2016	Cushing disease due to pituitary adenoma	Corcept Therapeutics	Withdrawn	No outcome recorded
Phase 3	NCT01795599	May 2013 → Feb 2015	—	Assistance Publique Hopitaux De Marseille	Unknown	No outcome recorded
Phase 3	NCT01436279	Jul 2011 → Aug 2013	—	Boston University	Completed	No outcome recorded
Phase 3	NCT00957346	Feb 2011 → Jan 2012	—	Gynuity Health Projects	Terminated	No outcome recorded
Phase 3	NCT01371565	Nov 2010 → Jun 2012	Cushing disease due to pituitary adenoma	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00936741	Jul 2009 → Sep 2012	Cushing syndrome	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00920465	Jun 2009 → Dec 2011	—	Western Galilee Hospital-Nahariya	Unknown	No outcome recorded
Phase 3	NCT00569582	Dec 2007 → Jan 2011	Cushing syndrome	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00867360	Aug 2005 → May 2009	depressive disorder, psychotic disorder	Stanford University	Terminated	No outcome recorded
Phase 3	NCT00128505	Aug 2005 → Nov 2006	major depressive disorder, psychotic disorder	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00208156	May 2005 → Nov 2006	major depressive disorder	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00146523	May 2005 → Jul 2006	major depressive disorder	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00130676	Sep 2004 → Jun 2006	major depressive disorder, psychotic disorder	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00128479	Sep 2004 → Jan 2007	major depressive disorder, psychotic disorder	Corcept Therapeutics	Completed	No outcome recorded
Phase 3	NCT00133705	Jul 2003 → Jun 2010	leiomyoma	University of Rochester	Completed	No outcome recorded
Phase 3	NCT03015701	Aug 1992 → Oct 2001	meningioma	SWOG Cancer Research Network	Completed	No outcome recorded

Phase 434 trials
Phase 4	NCT07671989	Jun → Dec 2026 expected	menstrual disorder	University of California, San Francisco	Recruiting	No outcome recorded
Phase 4	NCT05772169	Mar 2023 → Nov 2024	Cushing syndrome, type 2 diabetes mellitus	Corcept Therapeutics	Completed	No outcome recorded
Phase 4	NCT05119439	Oct 2022 → Jun 2023	—	Gynuity Health Projects	Terminated	No outcome recorded
Phase 4	NCT05322252	Jul 2022 → Jun 2025	pregnancy disorder with abortive outcome, preterm premature rupture of the membranes	Washington University School of Medicine	Completed	No outcome recorded
Phase 4	NCT05124314	Oct 2021 → Oct 2023	—	Clinical Hospital Merkur	Unknown	No outcome recorded
Phase 4	NCT05046041	Nov 2020 → Aug 2021	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT04458558	Jun 2020 → Apr 2021	pregnancy disorder	Center for Information and Counseling on Reproductive Health - Tanadgoma	Unknown	No outcome recorded
Phase 4	NCT03913104	Jan 2020 → Jul 2023	pregnancy disorder	Daniel Grossman, MD	Completed	No outcome recorded
Phase 4	NCT03829696	Jan 2020 → Jan 2021	—	University of California, San Francisco	Withdrawn	No outcome recorded
Phase 4	NCT04063904	Oct 2019 → Apr 2020	—	Gynuity Health Projects	Terminated	No outcome recorded
Phase 4	NCT03212352	Jun 2018 → Jan 2020	pregnancy disorder with abortive outcome	Radboud University Medical Center	Terminated	No outcome recorded
Phase 4	NCT03320057	Jun 2018 → Jul 2020	pregnancy disorder	Daniel Grossman	Completed	No outcome recorded
Phase 4	NCT03346629	Dec 2017 → Dec 2018	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT03210324	Jun 2017 → Jan 2019	leiomyoma	China Resources Zizhu Pharmaceutical Co., Ltd.	Terminated	No outcome recorded
Phase 4	NCT03044093	Jan 2017 → Jan 2019	—	Rambam Health Care Campus	Unknown	No outcome recorded
Phase 4	NCT02981030	Nov 2016 → Jun 2017	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT02745093	Sep → Dec 2016	—	Ibis Reproductive Health	Unknown	No outcome recorded
Phase 4	NCT02704481	Jun 2016 → Jan 2019	—	Gynuity Health Projects	Terminated	No outcome recorded
Phase 4	NCT02342002	Jan 2015 → Dec 2018	pregnancy disorder with abortive outcome	Gynuity Health Projects	Terminated	No outcome recorded
Phase 4	NCT02314754	Dec 2014 → Apr 2016	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT02720991	Jul 2014 → Apr 2015	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01990560	Nov 2013 → Sep 2016	adrenal gland hyperfunction	Icahn School of Medicine at Mount Sinai	Completed	No outcome recorded
Phase 4	NCT01856985	Apr → Sep 2013	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01768299	Feb 2013 → May 2014	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01798017	Nov 2012 → Jun 2015	menstrual disorder	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01631682	Nov 2010 → Jan 2015	post-traumatic stress disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00997347	Jul 2009 → Feb 2012	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01387256	May 2009 → Jul 2010	—	Gynuity Health Projects	Completed	No outcome recorded
Phase 4	NCT01490697	Mar 2009 → Sep 2015	post-traumatic stress disorder	Roger K. Pitman, MD	Completed	No outcome recorded
Phase 4	NCT00691067	May 2008 → Aug 2012	persian gulf syndrome	Bronx Veterans Medical Research Foundation, Inc	Completed	No outcome recorded
Phase 4	NCT00177372	Jan → Sep 2005	pregnancy disorder with abortive outcome	University of Pittsburgh	Completed	No outcome recorded
Phase 4	NCT00410345	Aug 2004 → May 2008	—	Hadassah Medical Organization	Completed	No outcome recorded
Phase 4	NCT00269568	Jun 2004 → Apr 2006	—	University of Pittsburgh	Completed	No outcome recorded
Phase 4	NCT00190294	Apr 2003 → Sep 2006	pregnancy disorder	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded

Phase not applicable27 trials
—	NCT05898321	Jun 2023 → Dec 2024	submucous uterine fibroid	Women's Hospital School Of Medicine Zhejiang University	Unknown	No outcome recorded
—	NCT05049980	Nov 2021 → Feb 2022	—	University Hospital, Toulouse	Completed	No outcome recorded
—	NCT03440866	Mar 2018 → Dec 2021	—	HaEmek Medical Center, Israel	Unknown	No outcome recorded
—	NCT03043014	Jun 2017 → Mar 2019	—	Assistance Publique Hopitaux De Marseille	Completed	No outcome recorded
—	NCT02651844	Apr 2016 → Oct 2019	breast cancer	Hospital Provincial Magdalena V. de Martínez	Completed	No outcome recorded
—	NCT02679092	Apr 2016 → Feb 2020	—	Stanford University	Withdrawn	No outcome recorded
—	NCT01862991	Jul 2013 → Jun 2016	—	Stanford University	Completed	No outcome recorded
—	NCT01811056	Apr 2013 → Jul 2014	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT01636063	Jun 2012 → May 2014	—	Boston University	Terminated	No outcome recorded
—	NCT01615731	May 2012 → Jun 2013	—	Stanford University	Completed	No outcome recorded
—	NCT01475318	Oct 2011 → Jun 2012	—	The University of Hong Kong	Unknown	No outcome recorded
—	NCT02219100	Nov 2010 → Nov 2011	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT02398838	Dec 2009 → Apr 2012	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00986921	Oct 2009 → Mar 2011	—	Boston University	Completed	No outcome recorded
—	NCT00969982	Jun 2009 → Jun 2013	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT01173003	Jun 2009 → Dec 2011	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00994734	May 2009 → Feb 2011	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00832871	Nov 2008 → Dec 2015	cancer	New Mexico Cancer Research Alliance	Terminated	No outcome recorded
—	NCT00784186	Aug 2008 → Aug 2009	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00680394	Jul 2007 → May 2008	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00468299	Apr 2007 → Dec 2008	pregnancy disorder with abortive outcome	Boston University	Terminated	No outcome recorded
—	NCT00386282	Sep 2006 → Mar 2011	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00382538	Mar 2005 → Nov 2006	—	Boston University	Completed	No outcome recorded
—	NCT00677755	Oct 2004 → Sep 2007	—	Taizhou Hospital	Completed	No outcome recorded
—	NCT01224509	Sep 2004 → Mar 2005	—	University of Southern California	Terminated	No outcome recorded
—	NCT00383032	Jan 2004 → Jun 2006	—	Dartmouth-Hitchcock Medical Center	Completed	No outcome recorded
—	NCT00186056	Jan 2003 → May 2007	major depressive disorder	Stanford University	Completed	No outcome recorded

Also used as a comparator or background therapy in 32 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 01 trial
Phase 0	NCT03248713 Comparator	Nov 2017 → May 2019	nicotine dependence	Yale University	Terminated	No outcome recorded
Phase 11 trial
Phase 1	NCT00579475 Comparator	Nov 2004 → Jun 2007	benign neoplasm of corpus uteri	Karolinska Institutet	Completed	No outcome recorded
Phase 1/23 trials
Phase 1/2	NCT03774745 Background	Feb → Jul 2019	—	University of California, Davis	Terminated	No outcome recorded
Phase 1/2	NCT02989662 Comparator	Sep 2017 → Jan 2024	alcohol-related disorders	Johns Hopkins University	Completed	No outcome recorded
Phase 1/2	NCT02243709 Comparator	Sep 2014 → Dec 2021	alcohol-related disorders	Brown University	Completed	No outcome recorded
Phase 24 trials
Phase 2	NCT02179749 Comparator	Sep 2014 → Nov 2019	alcohol abuse, alcohol dependence	The Scripps Research Institute	Completed	No outcome recorded
Phase 2	NCT01548417 Comparator	Mar 2012 → Jul 2015	alcohol dependence	The Scripps Research Institute	Completed	No outcome recorded
Phase 2	NCT00359125 Comparator	Jul 2006 → Dec 2010	bipolar depression	University of British Columbia	Withdrawn	No outcome recorded
Phase 2	NCT00352911 Comparator	Jul 2006 → Jun 2007	HIV infectious disease	VGX Pharmaceuticals, LLC	Completed	No outcome recorded
Phase 2/31 trial
Phase 2/3	NCT01134198 Comparator	May 2010 → Sep 2016	cocaine dependence	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 37 trials
Phase 3	NCT05839899 Background	Aug 2023 → Jul 2024	—	Planned Parenthood League of Massachusetts	Unknown	No outcome recorded
Phase 3	NCT05097326 Comparator	Jun 2022 → Apr 2023	—	Stanford University	Completed	No outcome recorded
Phase 3	NCT05304273 Comparator	May 2022 → Jul 2024	pregnancy disorder with abortive outcome	Calcutta National Medical College and Hospital	Completed	No outcome recorded
Phase 3	NCT03065660 Comparator	Sep 2017 → Jan 2020	—	University of Birmingham	Completed	No outcome recorded
Phase 3	NCT02633761 Comparator	Apr 2015 → Dec 2018	pregnancy disorder with abortive outcome	Gynuity Health Projects	Terminated	No outcome recorded
Phase 3	NCT02012491 Comparator	Jan 2014 → May 2017	pregnancy disorder with abortive outcome	University of Pennsylvania	Completed	No outcome recorded
Phase 3	NCT00637494 Comparator	Mar 2008 → Jun 2014	major depressive disorder, psychotic disorder	Corcept Therapeutics	Terminated	No outcome recorded

Phase 48 trials
Phase 4	NCT07174856 Comparator	Oct 2025 → Jan 2027 expected	—	Ibis Reproductive Health	Not yet recruiting	No outcome recorded
Phase 4	NCT05341817 Comparator	Nov 2022 → Aug 2025 overdue	—	KK Women's and Children's Hospital	Recruiting	No outcome recorded
Phase 4	NCT03134183 Background	Nov 2016 → Aug 2017	—	Virginia Commonwealth University	Completed	No outcome recorded
Phase 4	NCT02620904 Comparator	Jul 2016 → Oct 2019	pregnancy disorder with abortive outcome	Montefiore Medical Center	Terminated	No outcome recorded
Phase 4	NCT02708446 Comparator	May 2014 → Dec 2016	—	Gynuity Health Projects	Unknown	No outcome recorded
Phase 4	NCT01920022 Background	Oct 2013 → Oct 2015	—	Karolinska Institutet	Completed	No outcome recorded
Phase 4	NCT02412618 Comparator	Sep 2012 → Jan 2014	—	Medstar Health Research Institute	Completed	No outcome recorded
Phase 4	NCT00784797 Comparator	Jan 2009 → Jun 2012	—	Hadassah Medical Organization	Completed	No outcome recorded

Phase not applicable7 trials
—	NCT07646275 Comparator	Apr 2025 → Jan 2026	habitual spontaneous abortion, pregnancy disorder with abortive outcome, pregnancy loss, recurrent, 4	Harran University	Completed	No outcome recorded
—	NCT06733727 Comparator	Dec 2024 → Dec 2027 expected	—	The University of Hong Kong	Not yet recruiting	No outcome recorded
—	NCT04751500 Comparator	Jan 2021 → Nov 2022	—	Birmingham Women's and Children's NHS Foundation Trust	Completed	No outcome recorded
—	NCT00482209 Comparator	May 2007 → Oct 2009	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00286208 Comparator	Aug 2005 → Jan 2008	—	Gynuity Health Projects	Completed	No outcome recorded
—	NCT00285818 Comparator	Jan 2003 → Jan 2009	major depressive disorder	Stanford University	Completed	No outcome recorded
—	NCT00945997 Comparator	Oct 2000 → Sep 2004	—	Academic Medical Center - University of Amsterdam	Completed	No outcome recorded

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 174 sources stand behind the page.

Field	Value	Cited text
Known as	Mifépristone	“Mifepristone 200mg orally 20-24 hours prior and misoprostol 400mcg (two 200mcg tablets) vaginally 1-2 hours prior and placebo (buccal mint powder) buccally 1-2 hours prior to D&E” NCT03134183 ↗ 172 “This mixed-methods study follows a prospective cohort of participants receiving Mifeprex® (mifepristone) by a clinician in advance of a potential unintended pregnancy.” NCT03829696 ↗ “Participants were randomized to receive cervical priming with 200 mg of oral mifepristone 36 hours or 400 micrograms buccal misoprostol 3 hours before surgery.” PMID 33957651 ↗ Jun 2021 “the recommended use of mifepristone or misoprostol as cervical preparation for the abortions after 12 weeks” NCT01795599 ↗ “The first regimen will include a 200 mg oral dose of mifepristone followed by 800 mcg buccal misoprostol.” NCT01387256 ↗ “The antiprogesterone, mifepristone, is one of the most promising drugs that have been tested.” NCT00579475 ↗ “Administration of oral Mifepristone 600 mg and oral Misoprostol 400 mcg concomitantly.” NCT03440866 ↗ “mifepristone (200mg orally) followed 24-48 hours later by misoprostol” NCT07174856 ↗ “oral administration of mifepristone 200 mg” NCT00945997 ↗ “Mifépristone versus Misoprostol” NCT03043014 ↗ “Mifepristone” NCT00359125 ↗ “mifepristone” NCT04751500 ↗ NCT05046041 ↗ NCT00359125 ↗ NCT06492889 ↗ NCT06394999 ↗ NCT01768299 ↗ NCT03774745 ↗ NCT03212352 ↗ NCT01371565 ↗ NCT00505739 ↗ NCT00784186 ↗ NCT00752843 ↗ NCT03210324 ↗ NCT01631682 ↗ NCT05119439 ↗ NCT00592215 ↗ NCT00994734 ↗ NCT01786226 ↗ NCT00330993 ↗ NCT00455442 ↗ NCT01990560 ↗ NCT02788981 ↗ NCT02633761 ↗ NCT00459290 ↗ NCT00177372 ↗ NCT00352911 ↗ NCT04254627 ↗ NCT00383032 ↗ NCT06502158 ↗ NCT01548417 ↗ NCT06733727 ↗ NCT05304273 ↗ NCT00146523 ↗ NCT00712595 ↗ NCT01988610 ↗ NCT05839899 ↗ NCT02014337 ↗ NCT03259542 ↗ NCT00997347 ↗ NCT05177510 ↗ NCT00680394 ↗ NCT00133705 ↗ NCT05151016 ↗ NCT00832871 ↗ NCT02398838 ↗ NCT02046421 ↗ NCT01212588 ↗ NCT03913104 ↗ NCT04676776 ↗ NCT02271958 ↗ NCT02179749 ↗ NCT00691067 ↗ NCT00554177 ↗ NCT05341817 ↗ NCT03520439 ↗ NCT01636063 ↗ NCT00190294 ↗ NCT01436279 ↗ NCT01898312 ↗ NCT01493310 ↗ NCT00130676 ↗ NCT03269279 ↗ NCT02342002 ↗ NCT04063904 ↗ NCT02099825 ↗ NCT00833339 ↗ NCT05772169 ↗ NCT01419535 ↗ NCT02314754 ↗ NCT00285818 ↗ NCT03258372 ↗ NCT01920022 ↗ NCT06616077 ↗ NCT02981030 ↗ NCT07506512 ↗ NCT02243709 ↗ NCT01862991 ↗ NCT03320057 ↗ NCT06099769 ↗ NCT01811056 ↗ NCT01224509 ↗ NCT00099645 ↗ NCT00186056 ↗ NCT00382538 ↗ NCT00482209 ↗ NCT00721201 ↗ NCT00140478 ↗ NCT03044093 ↗ NCT00286208 ↗ NCT00881140 ↗ NCT02679092 ↗ NCT02012491 ↗ NCT04255498 ↗ NCT00128479 ↗ NCT01134198 ↗ NCT00784797 ↗ NCT03714880 ↗ NCT00468299 ↗ NCT01931657 ↗ NCT02651844 ↗ NCT05124314 ↗ NCT02354170 ↗ NCT00936741 ↗ NCT00957346 ↗ NCT02012296 ↗ NCT02620904 ↗ NCT03065660 ↗ NCT03248713 ↗ NCT02219100 ↗ NCT00043654 ↗ NCT00677755 ↗ NCT00422201 ↗ NCT06689254 ↗ NCT04458558 ↗ NCT03508635 ↗ NCT02704481 ↗ NCT00219778 ↗ NCT04588688 ↗ NCT03972358 ↗ NCT01739335 ↗ NCT01138553 ↗ NCT00986921 ↗ NCT00208156 ↗ NCT01798017 ↗ NCT00886873 ↗ NCT02720991 ↗ NCT05016349 ↗ NCT02708446 ↗ NCT00637494 ↗ NCT02642939 ↗ NCT01475318 ↗ NCT01490697 ↗ NCT03015701 ↗ NCT00725270 ↗ NCT01615731 ↗ NCT01333098 ↗ NCT00269568 ↗ NCT00867360 ↗ NCT05322252 ↗ NCT05898321 ↗ NCT00969982 ↗ NCT03225547 ↗ NCT02989662 ↗ NCT00698022 ↗ NCT03052400 ↗ NCT00128505 ↗ NCT07671989 ↗ NCT00569582 ↗ NCT05217758 ↗ NCT03346629 ↗ NCT02412618 ↗ NCT01294319 ↗ NCT00386282 ↗ NCT00410345 ↗ NCT01856985 ↗ NCT01173003 ↗ NCT05097326 ↗ NCT00105105 ↗ NCT02745093 ↗ NCT07646275 ↗ NCT01925092 ↗ NCT02985229 ↗
Known as	C-1073	“The purpose of this study is to evaluate the effects of C-1073 (Mifepristone) on cognition in patients with Alzheimer's disease (AD) who are also taking an acetylcholinesterase...” NCT00105105 ↗
Known as	Corlux	“Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol.” NCT00208156 ↗ 4 “Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol.” NCT00128479 ↗ “Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol.” NCT00146523 ↗ “Corlux (mifepristone) is a new medication” NCT00128505 ↗ “CORLUX (TM) (Mifepristone)” NCT00752843 ↗
Known as	Korlym	“Mifepristone 300 MG [Korlym]” NCT05772169 ↗ 1 “Korlym (mifepristone)” NCT01548417 ↗
Known as	Medicane	“Medicane (mifepristone)” NCT00554177 ↗
Known as	MFP	“Mifepristone (MFP) is currently used for medical abortion and for the treatment of Cushing disease.” NCT02651844 ↗
Known as	Mifegyne	“Mifepristone (Mifegyne) 50 mg every other day for 3 months” NCT00579475 ↗ 3 “mifepristone, 50 mg (Mifegyne, Exelgyn, Paris, France)” NCT01898312 ↗ NCT00920465 ↗ NCT05049980 ↗
Known as	Mifeprex	“Patients will receive Mifeprex® (mifepristone) by pharmacy rather than standard care at clinic visit” NCT03320057 ↗ 1 NCT03829696 ↗
Known as	MifeprexⓇ	“Patients will have MifeprexⓇ (mifepristone) shipped to a preferred address via an online mail order pharmacy rather than standard care at clinic visit.” NCT03913104 ↗
Known as	Mifepristone tablets	“Mifepristone tablets is developed by the China Resources Zizhu Pharmaceutical Co., Ltd.” NCT03210324 ↗
Known as	Mifepristone, RU486	“Mifepristone, RU486” NCT06733727 ↗
Known as	RU-486	“the purpose of this study is to determine the anti-HIV activity and safety of 3 different doses of mifepristone (also known as VGX-410 and RU486) in HIV infected people.” NCT00099645 ↗ 6 “evaluates the effectiveness of mifepristone (RU 486) in rapidly reducing the symptoms associated with schizoaffective disorder.” NCT00725270 ↗ “Mifepristone, also known as RU-486, is a well-tolerated competitive progesterone receptor antagonist.” NCT05322252 ↗ “Mifepristone (RU-486) in Androgen Independent Prostate Cancer” NCT00140478 ↗ “mifepristone (RU-486), a glucocorticoid receptor antagonist” NCT00043654 ↗ “mifepristone (RU-486)” NCT00359125 ↗ “Mifepristone (RU-486)” NCT00867360 ↗
Known as	VGX-410	“the purpose of this study is to determine the anti-HIV activity and safety of 3 different doses of mifepristone (also known as VGX-410 and RU486) in HIV infected people.” NCT00099645 ↗ 1 “two doses of orally administered mifepristone (VGX-410) (300 and 600 mg)” NCT00352911 ↗
Action	Inhibit	“a glucocorticoid receptor antagonist” NCT00043654 ↗
Modality	Small molecule	“a 19 norsteroid with anti-progesterone and anti glucocorticoid activity” NCT03015701 ↗
Route	Oral	“Mifepristone 5 MG capsule taken once daily by mouth” NCT00133705 ↗