drugset / Trial / NCT02708446
A Comparison of Sublingual and Buccal Misoprostol Regimens After Mifepristone for Mid-trimester Abortion
Phase 4
Unknown
320 enrolled
Gynuity Health Projects
Clinic No. 2 of Tashkent Medical Academy · collabKathmandu Medical College and Teaching Hospital · collabLa Rabta Maternity Hospital · collabRepublican Institute of RH, Perinatology, and Ob/Gyn · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The primary goal of this study is to directly compare repeat doses of sublingual and buccal routes of 400 mcg misoprostol following mifepristone for second trimester abortion in order to determine if sublingual route confers an advantage with respect to efficacy and median time to complete abortion.
Timeline
- Start
- 2014-05
- Primary completion
- 2016-12
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Mifepristone | Small molecule | 200 mg | Oral |
| Comparator | Misoprostol | Other / unclassified | 400 ug | Intravenous |
Indications
No indication recorded.