Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages

Summary

Prospective interventional study where participants with non-viable pregnancy at 1st trimester will be randomized into two arms, one group will receive conventional treatment with oral mifepristone followed by misoprostol vaginally and another group will receive letrozole for three consecutive days followed by misoprostol vaginally in an attempt to terminate the pregnancy medically. Mean duration of induction to expulsion of product of conception and rate of complete abortion will be compared in two groups.

Timeline

Start

2022-05-05

Primary completion

2024-07-26

Completion

2024-10-01

Drugs

Indications