Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation

Phase 4 Completed 100 enrolled Medstar Health Research Institute

RandomizedParallel-groupTriple-blindTreatment

Summary

A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.

Timeline

Start: 2012-09
Primary completion: 2014-01
Completion: 2014-01

Publications

Casey FE, Ye PP, Perritt JD, Moreno-Ruiz NL, Reeves MF. A randomized controlled trial evaluating same-day mifepristone and misoprostol compared to misoprostol alone for cervical preparation prior to second-trimester surgical abortion. Contraception. 2016 Aug;94(2):127-33. doi: 10.1016/j.contraception.2016.02.032. Epub 2016 Mar 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Mifepristone	Small molecule	200 mg	Oral
Comparator	Misoprostol	Other / unclassified	400 ug	Intravenous

Indications

No indication recorded.