drugset / Trial / NCT06394999
Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive
Phase 3
Active not recruiting
615 enrolled
Leiden University Medical Center
Children's Investment Fund Foundation · collabKarolinska Institutet · collabWomen on Waves · collab
NaSingle-groupOpen-labelPrevention
Summary
Participants in the study will use mifepristone 50 mg once-a-week for one year as a contraceptive. With this, we want to confirm that the chances of getting pregnant while using this contraceptive are very small. We also want to demonstrate that the use of mifepristone is safe, and it does not lead to any severe health problems. We expect fewer side effects compared to other frequently used contraceptives with hormones. Mifepristone does not contain these hormones. It is important to know how people experience that use of one tablet a week.
Timeline
- Start
- 2025-05-02
- Primary completion
- 2027-06-01
- Completion
- 2028-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mifepristone | Small molecule | 50 mg | Oral |
Indications
No indication recorded.