drugset / Trial / NCT00410345

Cervical Rippening With Antiprogesterone in Midtrimester Abortions

NCT00410345

Phase 4 Completed 145 enrolled Hadassah Medical Organization
RandomizedParallel-groupOpen-labelTreatment

Summary

Induction of midtrimester abortion includes cervical ripening and then contraction to induce uterine evacuation. There are several protocols, but most of them include using prostaglandins (PG). The disadvantages of using PG include uncomfortable side effects and limits of using it for women after cesarean section. Mifepristone is an antiprogesterone drug and been used for induction of abortion in first and second trimesters abortions. The aim of this study is to explore the effectiveness of Mifepristone for cervical ripening before high dose Oxytocin drip.

Timeline

Start
2004-08
Primary completion
2008-05
Completion
2008-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Mifepristone Small molecule

Indications

No indication recorded.