drugset / Trial / NCT01134198

Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients

NCT01134198

Phase 2/3 Completed 58 enrolled New York State Psychiatric Institute
RandomizedParallel-groupTriple-blindTreatment

Summary

This research will evaluate the impact of blocking central and peripheral glucocorticoid receptors on stress sensitivity and the risk of relapse to cocaine use in treatment-seeking cocaine-dependent individuals. Mifepristone (RU-486) will be the glucocorticoid antagonist used.

Timeline

Start
2010-05
Primary completion
2016-09
Completion
2018-02-14

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mifepristone Small molecule 600 mg

Indications