drugset / Trial / NCT00385229
Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy
RandomizedParallel-groupOpen-labelPrevention
Summary
Post term pregnancy is a risk pregnancy. Aim of the study was to investigate whether induction of labor at gestational age 289(41 weeks+2 days) reduces neonatal morbidity compared to expectant management. Secondary aims was to assess the effect on mode of delivery and maternal complications, as well as assess women's views and experiences. Our 0-hypothesis was that induction of labor at gestational age 41+2 did not result in better outcome of pregnancy, measured as perinatal morbidity. Following inclusion, women were randomly allocated to induction of labor or to monitoring of pregnancy every third day until delivery
Timeline
- Start
- 2002-09
- Primary completion
- 2003-12
- Completion
- 2004-07
Publications
- Results Heimstad R, Skogvoll E, Mattsson LA, Johansen OJ, Eik-Nes SH, Salvesen KA. Induction of labor or serial antenatal fetal monitoring in postterm pregnancy: a randomized controlled trial. Obstet Gynecol. 2007 Mar;109(3):609-17. doi: 10.1097/01.AOG.0000255665.77009.94.
- Middleton P, Shepherd E, Morris J, Crowther CA, Gomersall JC. Induction of labour at or beyond 37 weeks' gestation. Cochrane Database Syst Rev. 2020 Jul 15;7(7):CD004945. doi: 10.1002/14651858.CD004945.pub5.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dinoprostone | Other / unclassified | — | — |
| Subject | Misoprostol | Other / unclassified | — | — |
| Subject | Oxytocin | Peptide | — | — |