drugset / Trial / NCT00108017
Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)
RandomizedCrossoverDouble-blindTreatment
Summary
This study is comparing 2 medications for glaucoma and how effective they are at controlling glaucoma over the course of an entire day.
Timeline
- Start
- 2005-04
- Primary completion
- 2006-07
- Completion
- 2006-07
Publications
- Background Feldman RM, Stewart RH, Stewart WC, Jia G, Smugar SS, Galet VA. 24-hour control of intraocular pressure with 2% dorzolamide/0.5% timolol fixed-combination ophthalmic solution in open-angle glaucoma. Curr Med Res Opin. 2008 Aug;24(8):2403-12. doi: 10.1185/03007990802243366. Epub 2008 Jul 14.
- Background Olander KW, Galet VA, Jia G, Smugar SS, Stewart WC. Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone. J Ocul Pharmacol Ther. 2009 Aug;25(4):357-64. doi: 10.1089/jop.2008.0104.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dorzolamide | Small molecule | — | — |
| Subject | Timolol | Other / unclassified | — | — |