drugset / Trial / NCT00110305

A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines

NCT00110305

Phase 2 Completed 368 enrolled Tibotec Pharmaceuticals, Ireland
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the dose-response relationship of antiviral activity after 48 weeks treatment with 3 different dose regimens of TMC278.

Timeline

Start
2005-06
Primary completion
2011-12
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Efavirenz Other / unclassified 600 mg
Subject Rilpivirine Small molecule 25 mg
Subject Rilpivirine Small molecule 75 mg
Subject Rilpivirine Small molecule 150 mg
Background Lamivudine Other / unclassified
Background Tenofovir disoproxil fumarate Small molecule
Background Zidovudine Small molecule
Background emtricitabine Other / unclassified