Magnesium Sulfate Versus Indomethacin for Preterm Labor

Phase 4 Terminated University of Pennsylvania

RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this study is to investigate the efficacy of Indomethacin compared to Magnesium Sulfate (MgSO4) in reducing neonatal morbidity through a prospective double blind randomized clinical trial. The specific aim of the project is to test the hypothesis that Indomethacin, compared to MgSO4, will decrease the proportion of neonates diagnosed with major complications or death.

Timeline

Start: 2003-02
Primary completion: 2006-02
Completion: 2006-02

Publications

Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, Papadopoulou A, Coomarasamy A, Tobias A, Chou D, Oladapo OT, Price MJ, Morris K, Gallos ID. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022 Aug 10;8(8):CD014978. doi: 10.1002/14651858.CD014978.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Indomethacin	Small molecule	—	—
Subject	Magnesium Sulfate	Other / unclassified	—	—

Indications

No indication recorded.