Treatment of Tennis Elbow With Botulinum Toxin

NCT00119704 ↗

Phase 3 Completed 60 enrolled Chinese University of Hong Kong New World Development Company Limited · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine whether Botulinum A toxin is effective in the treatment of tennis elbow (lateral epicondylitis).

Timeline

Start: 2002-09
Primary completion: —
Completion: 2005-03

Outcome

Met primary endpoint

paper Mean VAS scores for the botulinum group at baseline and at 4 weeks were 65.5 mm and 25.3 mm, respectively; respective scores for the placebo group were 66.2 mm and 50.5 mm PMID 16330790 ↗

paper between-group difference of changes, 24.4 mm [95% CI, 13.0 to 35.8 mm]; P < 0.001 PMID 16330790 ↗

Publications

Results Wong SM, Hui AC, Tong PY, Poon DW, Yu E, Wong LK. Treatment of lateral epicondylitis with botulinum toxin: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2005 Dec 6;143(11):793-7. doi: 10.7326/0003-4819-143-11-200512060-00007.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Botulinum toxin type A	Protein / enzyme biologic	60 iu	Other