drugset / Trial / NCT00122044
Childhood Hypertonia of Central Origin: A Trial of Anticholinergic Treatment Effects
Phase 2
Completed
35 enrolled
University of Southern California
Crowley Carter Foundation · collabDon and Linda Carter Foundation · collabUnited Cerebral Palsy Foundation · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This study is an open-label trial of trihexyphenidyl in children with upper extremity dystonia due to cerebral palsy. It is hypothesized that trihexyphenidyl in doses up to 0.75mg/kg/day would be well-tolerated and show significant changes on the Melbourne scale of upper extremity function.
Timeline
- Start
- 2003-01
- Primary completion
- 2004-12
- Completion
- 2004-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Trihexyphenidyl | Small molecule | 0.75 mg/kg | — |