drugset / Trial / NCT00125853
The Effect of Nebivolol on Insulin Sensitivity
RandomizedCrossoverSingle-blindTreatment
Summary
The purpose of this study is to conduct a randomised trial to compare the insulin sensitivity, 24 hour blood pressure profile, and tolerability of nebivolol plus a thiazide-like diuretic versus atenolol plus a thiazide-like diuretic.
Timeline
- Start
- 2006-07
- Primary completion
- 2009-01
- Completion
- 2009-01
Outcome
Missed primary endpoint
registry analysis (other test); Atenolol vs Nebivolol; p = 0.60; Linear Mixed effect Modelling, adjusted NCT00125853 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atenolol | Other / unclassified | 25 mg | — |
| Comparator | Nebivolol | Other / unclassified | 2.5 mg | — |