drugset / Trial / NCT00133679
Chronic Sildenafil for Severe Diaphragmatic Hernia
Phase 4
Terminated
9 enrolled
University of California, San Francisco
Ann & Robert H Lurie Children's Hospital of Chicago · collabChildren's Hospital Los Angeles · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to test if sildenafil is effective in the treatment of infants with severe congenital diaphragmatic hernia (determined by the presence of prolonged pulmonary hypertension or prolonged oxygen supplementation on mechanical ventilation), as measured by the estimated pulmonary artery systolic pressure following treatment.
Timeline
- Start
- 2006-02
- Primary completion
- 2013-07
- Completion
- 2013-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sildenafil | Unknown | 0.5 mg/kg | Oral |