Drugs / Sildenafil
Sildenafil
also known as
Sildenafil citrate · Viagra · Revatio · Hezkue · Integra · Respatio · ASP-001 · Bilayer Matrix Wound Dressing · +10 more
targets CYP3A4 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 9 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansions (5) | US (FDA) | REVATIO | — | 2009-05-07 – 2023-03-03 | fda.gov ↗ |
| Label expansions (2) | US (FDA) | VIAGRA | — | 2002-09-19 – 2014-03-11 | fda.gov ↗ |
| Approved | EU (EMA) | Viagra | — | 1998-09-13 | europa.eu ↗ |
| Approved | US (FDA) | VIAGRA | — | 1998-03-27 | fda.gov ↗ |
Trials 265 · started per year
today
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EU approved 1998
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 07 trials | ||||||
| Phase 0 | NCT07039760 | Aug 2026 → Feb 2028 expected | brain neoplasm | Washington University School of Medicine | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT05466695 | Aug 2022 → Jul 2023 | — | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT06527729 | Jul 2021 → Jun 2022 | alopecia areata | Assiut University | Completed | No outcome recorded |
| Phase 0 | NCT03229512 | Apr 2017 → Jun 2020 | hand-foot syndrome | Northwestern University | Completed | No outcome recorded |
| Phase 0 | NCT02795351 | Jun 2015 → Feb 2021 | migraine with aura | Herlev Hospital | Completed | No outcome recorded |
| Phase 0 | NCT01359670 | May 2011 → May 2013 | Duchenne muscular dystrophy | Cedars-Sinai Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT00815646 | Jan 2008 → Dec 2015 | high altitude pulmonary edema | Duke University | Completed | No outcome recorded |
| Phase 148 trials | ||||||
| Phase 1 | NCT07508358 | May 2026 → May 2027 expected | primary dysmenorrhea | Kevin Hellman | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07302698 | Mar → May 2026 overdue | — | Aspargo Labs, Inc | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07117383 | Jan → Mar 2026 overdue | erectile dysfunction | Aspargo Labs, Inc | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06289881 | Feb → Mar 2025 | — | Bio-innova Co., Ltd | Unknown | No outcome recorded |
| Phase 1 | NCT06782659 | Jan → Mar 2025 overdue | erectile dysfunction | Aspargo Labs, Inc | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06324396 | Mar 2024 → Dec 2026 expected | congenital cardiovascular shunt | Children's Mercy Hospital Kansas City | Recruiting | No outcome recorded |
| Phase 1 | NCT05684289 | Jan → May 2023 | — | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 1 | NCT05275725 | Jul 2022 → Jan 2025 overdue | perinatal asphyxia | Pia Wintermark | Active not recruiting | No outcome recorded |
| Phase 1 | NCT04283435 | Sep 2021 → Mar 2022 | — | Cairo University | Unknown | No outcome recorded |
| Phase 1 | NCT04211272 | Jan 2020 → Apr 2021 | — | Actelion | Completed | No outcome recorded |
| Phase 1 | NCT04169191 | Sep 2019 → Dec 2021 overdue | perinatal asphyxia | McGill University Health Centre/Research Institute of the McGill University Health Centre | Active not recruiting | No outcome recorded |
| Phase 1 | NCT04481789 | Oct → Dec 2018 | — | Shionogi | Completed | No outcome recorded |
| Phase 1 | NCT03510338 | May → Jun 2018 | erectile dysfunction | N4 Pharma UK Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT04994860 | Mar → Jun 2018 | pulmonary arterial hypertension | Bial - Portela C S.A. | Completed | No outcome recorded |
| Phase 1 | NCT03417492 | Mar 2018 → Jun 2022 | traumatic brain injury, traumatic encephalopathy | University of Pennsylvania | Terminated | No outcome recorded |
| Phase 1 | NCT02975037 | Feb → Mar 2017 | — | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 1 | NCT03028298 | Dec 2016 → Dec 2022 | intracranial vasospasm, subarachnoid hemorrhage | University of Mississippi Medical Center | Unknown | No outcome recorded |
| Phase 1 | NCT02946944 | Oct 2016 → Oct 2020 | pulmonary embolism | Meshalkin Research Institute of Pathology of Circulation | Unknown | No outcome recorded |
| Phase 1 | NCT02466802 | Jul 2015 → Jan 2019 | neoplasm | Virginia Commonwealth University | Completed | No outcome recorded |
| Phase 1 | NCT01954524 | May 2014 → Oct 2015 | cirrhosis of liver | University of Maryland, Baltimore | Terminated | No outcome recorded |
| Phase 1 | NCT02028598 | Jan → Mar 2014 | — | CTC Bio, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01986673 | Oct → Nov 2013 | — | Strategic Science & Technologies, LLC | Completed | No outcome recorded |
| Phase 1 | NCT01950923 | Sep 2013 → Mar 2016 | kidney cancer | Wake Forest University Health Sciences | Completed | No outcome recorded |
| Phase 1 | NCT02136329 | Jun 2013 → Dec 2014 | acute kidney injury | University of Leicester | Completed | No outcome recorded |
| Phase 1 | NCT01670136 | Feb 2013 → Jul 2016 | pulmonary hypertension, neonatal | University of North Carolina, Chapel Hill | Completed | No outcome recorded |
| Phase 1 | NCT01499498 | Dec 2012 → Apr 2013 | hepatitis C virus infection | Imperial College London | Completed | No outcome recorded |
| Phase 1 | NCT01656798 | Aug 2012 | — | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT02628847 | Mar 2012 → Oct 2016 | stroke disorder | University of Utah | Terminated | No outcome recorded |
| Phase 1 | NCT01580501 | Mar 2012 → Mar 2013 | Duchenne muscular dystrophy | Cedars-Sinai Medical Center | Completed | No outcome recorded |
| Phase 1 | NCT01651858 | Feb → Mar 2012 | — | Daewoong Pharmaceutical Co. LTD. | Completed | No outcome recorded |
| Phase 1 | NCT01514903 | Dec 2011 | erectile dysfunction | Hanmi Pharmaceutical Company Limited | Completed | No outcome recorded |
| Phase 1 | NCT01769638 | Sep → Nov 2011 | — | Seoul Pharma Co., Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT01375699 | Aug 2011 → Aug 2017 | breast cancer, digestive system cancer, female reproductive organ cancer, sarcoma | Virginia Commonwealth University | Completed | No outcome recorded |
| Phase 1 | NCT01254383 | Dec 2010 → Mar 2011 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01254396 | Dec 2010 → Jan 2011 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01244620 | Nov → Dec 2010 | pulmonary arterial hypertension | Pfizer | Terminated | No outcome recorded |
| Phase 1 | NCT01219023 | Jun 2010 → Apr 2012 | hand-foot syndrome | Duke University | Completed | No outcome recorded |
| Phase 1 | NCT00904748 | Jan → Mar 2010 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01027117 | Sep 2009 | — | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00950404 | Aug → Sep 2009 | — | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00795938 | Oct → Nov 2008 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00866463 | Oct 2008 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00814736 | Aug → Sep 2008 | erectile dysfunction, hyperplasia, overactive bladder | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT00767598 | Dec 2007 | — | Inje University | Completed | No outcome recorded |
| Phase 1 | NCT00452582 | Apr 2005 → ? | ischemic stroke | Henry Ford Health System | Terminated | No outcome recorded |
| Phase 1 | NCT00056433 | Mar 2003 → Dec 2006 | sickle cell disease | National Institutes of Health Clinical Center (CC) | Completed | No outcome recorded |
| Phase 1 | NCT00175981 | Feb 2003 → Nov 2004 | — | Heidelberg University | Completed | No outcome recorded |
| Phase 1 | NCT00223717 | Jan 2001 → Jan 2017 | hypertensive disorder | Vanderbilt University | Completed | No outcome recorded |
| Phase 1/213 trials | ||||||
| Phase 1/2 | NCT04489446 | Aug 2020 → Apr 2021 | COVID-19 | Universidad Nacional Andres Bello | Completed | No outcome recorded |
| Phase 1/2 | NCT04100759 | Jun 2019 | erectile dysfunction | Ain Shams University | Completed | No outcome recorded |
| Phase 1/2 | NCT03259516 | May 2017 → Dec 2018 | myelodysplastic syndrome | St. Petersburg State Pavlov Medical University | Terminated | No outcome recorded |
| Phase 1/2 | NCT03012386 | Jan 2017 → Jul 2021 | — | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 1/2 | NCT02626182 | Dec 2015 → Jan 2018 | cystic fibrosis | National Jewish Health | Completed | No outcome recorded |
| Phase 1/2 | NCT03192709 | Feb 2015 → Aug 2017 | female infertility | Royan Institute | Unknown | No outcome recorded |
| Phase 1/2 | NCT01853540 | Jan 2013 → Oct 2014 | pulmonary non-tuberculous mycobacterial infection | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1/2 | NCT01194232 | Aug → Dec 2012 | cystic fibrosis | Children's Hospital Medical Center, Cincinnati | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT02028429 | Jul 2012 → Nov 2013 | hepatic encephalopathy | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 1/2 | NCT01334554 | Apr 2011 → Aug 2013 | metabolic syndrome X, obesity disorder | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 1/2 | NCT01290484 | Dec 2010 → Apr 2013 | lymphangioma | Stanford University | Completed | No outcome recorded |
| Phase 1/2 | NCT00659529 | Aug 2008 → Aug 2012 | cystic fibrosis | National Jewish Health | Completed | No outcome recorded |
| Phase 1/2 | NCT00123162 | May 2007 → Jun 2011 | dysmenorrhea | Milton S. Hershey Medical Center | Completed | No outcome recorded |
| Phase 251 trials | ||||||
| Phase 2 | NCT07647003 | Oct 2026 → May 2027 expected | hypertensive disorder | NuSirt Biopharma | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06810284 | Oct 2026 → Jun 2027 expected | brain hypoxia - ischemia | Assistance Publique - Hôpitaux de Paris | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT07290400 | Apr → Jun 2026 overdue | erectile dysfunction | Aspargo Labs, Inc | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT05061368 | Mar 2022 → May 2027 expected | chronic obstructive pulmonary disease | University of Alberta | Recruiting | No outcome recorded |
| Phase 2 | NCT04797286 | Sep 2021 → Sep 2026 expected | pulmonary hypertension, scleroderma | Johns Hopkins University | Recruiting | No outcome recorded |
| Phase 2 | NCT04565925 | Jul 2021 → Dec 2026 expected | spinal cord injury | The University of Texas Medical Branch, Galveston | Recruiting | No outcome recorded |
| Phase 2 | NCT04985929 | Jul 2021 → Jul 2024 | — | University of Alberta | Completed | No outcome recorded |
| Phase 2 | NCT04948151 | Jun → Dec 2021 | sexual disorder | Strategic Science & Technologies, LLC | Unknown | No outcome recorded |
| Phase 2 | NCT04058132 | Aug 2019 → Mar 2020 | traumatic brain injury | Uniformed Services University of the Health Sciences | Terminated | No outcome recorded |
| Phase 2 | NCT03855332 | Jul 2019 → Dec 2022 | cerebrovascular disorder | University of Oxford | Completed | No outcome recorded |
| Phase 2 | NCT03696758 | Oct 2018 → Feb 2020 | pulmonary immaturity | University of Wisconsin, Madison | Completed | No outcome recorded |
| Phase 2 | NCT04718233 | Sep 2018 → Jul 2019 | pregnancy loss, recurrent, 4 | Ain Shams University | Completed | No outcome recorded |
| Phase 2 | NCT03142568 | Apr 2018 → Mar 2025 | bronchopulmonary dysplasia | University of North Carolina, Chapel Hill | Completed | No outcome recorded |
| Phase 2 | NCT03364335 | Jan → Aug 2018 | obesity disorder | NuSirt Biopharma | Completed | No outcome recorded |
| Phase 2 | NCT02908490 | Apr 2017 → Jun 2020 | atherosclerosis, rheumatoid arthritis | Kimberly Liang | Terminated | No outcome recorded |
| Phase 2 | NCT02951429 | Dec 2016 → Sep 2019 | idiopathic pulmonary fibrosis | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2 | NCT02663830 | Jan 2016 → Jan 2017 | anovulation | Ain Shams University | Completed | No outcome recorded |
| Phase 2 | NCT02546609 | Nov 2015 → Nov 2016 | NAFLD1 | NuSirt Biopharma | Completed | No outcome recorded |
| Phase 2 | NCT02571101 | Nov 2015 → May 2016 | premature ejaculation | CTC Bio, Inc. | Unknown | No outcome recorded |
| Phase 2 | NCT01132482 | Oct 2015 → May 2017 | cystic fibrosis | National Jewish Health | Completed | No outcome recorded |
| Phase 2 | NCT02570282 | Sep 2015 → May 2017 | sexual disorder | Strategic Science & Technologies, LLC | Completed | No outcome recorded |
| Phase 2 | NCT02335242 | May 2015 → Mar 2021 | lymphatic malformation | Stanford University | Completed | No outcome recorded |
| Phase 2 | NCT02244528 | Oct 2014 → Oct 2016 | — | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 2 | NCT02057458 | Apr 2014 → Jul 2018 | cystic fibrosis | Augusta University | Completed | No outcome recorded |
| Phase 2 | NCT01817751 | Apr 2013 → Aug 2020 | brain neoplasm, glioblastoma, grade III glioma | Virginia Commonwealth University | Completed | No outcome recorded |
| Phase 2 | NCT01830790 | Mar 2013 → May 2014 | age-related macular degeneration | Duke University | Terminated | No outcome recorded |
| Phase 2 | NCT01762475 | Jan 2013 → Dec 2015 | traumatic brain injury, traumatic encephalopathy | Uniformed Services University of the Health Sciences | Completed | No outcome recorded |
| Phase 2 | NCT01601470 | Sep 2012 → Jan 2013 | hypertensive disorder | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 2 | NCT01360671 | Mar 2012 → Apr 2013 | pulmonary hypertension, neonatal | Viatris Inc. | Withdrawn | No outcome recorded |
| Phase 2 | NCT01481350 | Feb 2012 → Jun 2013 | pulmonary hypertension | University of Turin, Italy | Completed | No outcome recorded |
| Phase 2 | NCT01350154 | Nov 2011 → Apr 2013 | Becker muscular dystrophy | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 2 | NCT01432665 | Sep 2011 → May 2013 | hypoactive sexual desire disorder | Emotional Brain NY Inc. | Completed | No outcome recorded |
| Phase 2 | NCT01409031 | Jul 2011 → Oct 2013 | pulmonary hypertension, respiratory failure | University of Colorado, Denver | Terminated | No outcome recorded |
| Phase 2 | NCT01069861 | Dec 2010 → Nov 2011 | pulmonary hypertension, neonatal, respiratory failure | Viatris Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT01168908 | Sep 2010 → Jan 2014 | Becker muscular dystrophy, Duchenne muscular dystrophy | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT01091870 | Mar 2010 → Dec 2012 | brain aneurysm, intracranial vasospasm, subarachnoid hemorrhage | Hospital de Clinicas de Porto Alegre | Withdrawn | No outcome recorded |
| Phase 2 | NCT00914277 | May → Sep 2009 | erectile dysfunction | Sanofi | Completed | No outcome recorded |
| Phase 2 | NCT00871065 | Jul 2008 → Feb 2009 | intracranial vasospasm, subarachnoid hemorrhage | University of Nebraska | Withdrawn | No outcome recorded |
| Phase 2 | NCT00940901 | Jun 2008 → Nov 2012 | priapism, sickle cell disease | Johns Hopkins University | Completed | No outcome recorded |
| Phase 2 | NCT00492531 | Jun 2007 → Sep 2009 | pulmonary hypertension, sickle cell disease | National Heart, Lung, and Blood Institute (NHLBI) | Terminated | No outcome recorded |
| Phase 2 | NCT00359736 | Jul 2006 → Oct 2008 | pulmonary fibrosis, pulmonary hypertension | VA Office of Research and Development | Completed | No outcome recorded |
| Phase 2 | NCT00273416 | Jan 2006 → ? | erectile dysfunction | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT00165295 | Sep 2005 → Jun 2007 | Waldenstrom macroglobulinemia | Dana-Farber Cancer Institute | Completed | No outcome recorded |
| Phase 2 | NCT00352482 | Nov 2004 → Jul 2007 | idiopathic pulmonary fibrosis, pulmonary hypertension | National Heart, Lung, and Blood Institute (NHLBI) | Completed | No outcome recorded |
| Phase 2 | NCT00141310 | Sep 2004 → Apr 2006 | preeclampsia | Viatris Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT00640458 | Apr 2004 → Mar 2007 | sexual disorder | Viatris Inc. | Completed | No outcome recorded |
| Phase 2 | NCT00317421 | Mar 2004 → Nov 2005 | hypertensive disorder | University of Edinburgh | Completed | No outcome recorded |
| Phase 2 | NCT00624273 | Feb → Nov 2004 | ulcer disease | Charite University, Berlin, Germany | Completed | No outcome recorded |
| Phase 2 | NCT00145938 | Sep 2003 → Sep 2006 | pulmonary hypertension | University of Chicago | Terminated | No outcome recorded |
| Phase 2 | NCT00746967 | Jan 2003 → Feb 2004 | psychosexual disorder | Viatris Inc. | Completed | No outcome recorded |
| Phase 2 | NCT02162979 | Feb 2002 → Jan 2009 | Parkinson disease | Loma Linda University | Terminated | No outcome recorded |
| Phase 2/314 trials | ||||||
| Phase 2/3 | NCT06800092 | Jun 2027 → Jun 2030 expected | cancer | The University of Texas Medical Branch, Galveston | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT07462260 | Aug 2025 → Apr 2026 overdue | pulmonary hypertension, rheumatic heart disease | Sindh Institute of Cardiovascular Diseases | Recruiting | No outcome recorded |
| Phase 2/3 | NCT05971667 | Jul → Oct 2023 | — | Beni-Suef University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05951413 | Jun → Sep 2023 | — | Beni-Suef University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05846906 | Oct 2021 → Apr 2022 | female infertility | Beni-Suef University | Completed | No outcome recorded |
| Phase 2/3 | NCT03763045 | Dec 2018 → Feb 2019 | pulmonary hypertension | Ain Shams University | Unknown | No outcome recorded |
| Phase 2/3 | NCT03476876 | Apr 2018 → Oct 2020 | ulcer of lower limbs | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 2/3 | NCT02782559 | Jul 2016 → Jul 2017 | preeclampsia | The University of Texas Health Science Center, Houston | Withdrawn | No outcome recorded |
| Phase 2/3 | NCT02435303 | May 2016 → Jun 2018 | mitral valve disorder, pulmonary hypertension | Asan Medical Center | Terminated | No outcome recorded |
| Phase 2/3 | NCT02766725 | Jan → Nov 2015 | infertility disorder | Assiut University | Completed | No outcome recorded |
| Phase 2/3 | NCT02050360 | Nov 2013 → May 2015 | Raynaud disease | University Hospital, Grenoble | Completed | No outcome recorded |
| Phase 2/3 | NCT01936350 | Sep → Nov 2013 | heart failure | Hospital Ana Nery | Completed | No outcome recorded |
| Phase 2/3 | NCT00981747 | Sep 2009 → Dec 2016 | idiopathic pulmonary fibrosis, pulmonary fibrosis | Alicia Gerke | Terminated | No outcome recorded |
| Phase 2/3 | NCT01107782 | Jun 2008 → Jun 2010 | fetal growth restriction | Tehran University of Medical Sciences | Unknown | No outcome recorded |
| Phase 333 trials | ||||||
| Phase 3 | NCT05490680 | Jan → Dec 2024 | erectile dysfunction | IBSA Institut Biochimique SA | Completed | No outcome recorded |
| Phase 3 | NCT03997097 | Jun 2023 → Jun 2026 | pulmonary hypertension, univentricular heart | University Hospital, Montpellier | Withdrawn | No outcome recorded |
| Phase 3 | NCT03686306 | Nov 2021 → Nov 2025 overdue | peripheral arterial disease | Rennes University Hospital | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04304313 | Feb → Mar 2020 | COVID-19 | Tongji Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04052269 | Jun 2019 → Oct 2021 | glaucoma | Imperial College London | Suspended | No outcome recorded |
| Phase 3 | NCT03356353 | Mar 2018 → Sep 2021 | advanced heart failure | University of Calgary | Unknown | No outcome recorded |
| Phase 3 | NCT03154476 | Jul 2017 → Jun 2019 | cirrhosis of liver, congenital heart disease | Mayo Clinic | Completed | No outcome recorded |
| Phase 3 | NCT03230162 | Jun 2017 → May 2018 | fetal growth restriction | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT03177824 | Mar → Sep 2017 | fetal growth restriction | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT02832570 | Nov 2016 → Oct 2017 | peripheral arterial occlusive disease 1 | University Hospital, Angers | Completed | No outcome recorded |
| Phase 3 | NCT02590536 | Oct 2015 → Jun 2017 | fetal growth restriction | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT01913847 | Sep 2013 → Dec 2018 | pulmonary hypertension, systolic heart failure | Hanmi Pharmaceutical Company Limited | Unknown | No outcome recorded |
| Phase 3 | NCT01720524 | Aug 2013 → Oct 2018 | pulmonary hypertension, neonatal | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT01091012 | Sep 2011 → Dec 2012 | pulmonary hypertension | Hospital Universitari Vall d'Hebron Research Institute | Unknown | No outcome recorded |
| Phase 3 | NCT01392469 | Apr 2011 → Oct 2012 | pulmonary arterial hypertension | Novartis Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00796510 | Jul 2010 → Jan 2011 | pulmonary arterial hypertension | Pfizer | Terminated | No outcome recorded |
| Phase 3 | NCT00796666 | May 2009 → Mar 2011 | pulmonary arterial hypertension | Pfizer | Terminated | No outcome recorded |
| Phase 3 | NCT00763867 | Sep 2008 → Sep 2012 | diastolic heart failure | Duke University | Completed | No outcome recorded |
| Phase 3 | NCT00734604 | Aug 2008 → Sep 2009 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 3 | NCT00742014 | Aug 2008 → Aug 2011 | hypertensive disorder | The Hospital for Sick Children | Terminated | No outcome recorded |
| Phase 3 | NCT00454207 | Apr 2007 → Feb 2009 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00303004 | Mar 2006 → Jan 2008 | Eisenmenger syndrome | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 3 | NCT00544076 | Jan 2006 → Apr 2012 | erectile dysfunction, grade III prostatic intraepithelial neoplasia | City of Hope Medical Center | Terminated | No outcome recorded |
| Phase 3 | NCT00159874 | Jan 2004 → Dec 2012 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00407446 | Jan 2004 → Feb 2005 | heart failure | University of Milan | Completed | No outcome recorded |
| Phase 3 | NCT00159913 | Aug 2003 → Jun 2008 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00159861 | Jul 2003 → Jan 2006 | pulmonary hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00309790 | May 2003 → Mar 2006 | congestive heart failure | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT00159887 | Dec 2002 → Feb 2007 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00309816 | Dec 2001 → Feb 2006 | congestive heart failure | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 3 | NCT00527995 | Aug 2001 → Jun 2003 | type 2 diabetes mellitus | Ruhr University of Bochum | Completed | No outcome recorded |
| Phase 3 | NCT00420901 | Jan 1999 → Feb 2000 | diabetes mellitus | IRCCS San Raffaele | Completed | No outcome recorded |
| Phase 3 | NCT02930811 | ? → Oct 2022 | peripheral arterial occlusive disease 1 | University Hospital, Angers | Withdrawn | No outcome recorded |
| Phase 465 trials | ||||||
| Phase 4 | NCT06875258 | Jan 2024 → Jan 2027 expected | — | The Netherlands Cancer Institute | Recruiting | No outcome recorded |
| Phase 4 | NCT05183334 | Dec 2021 → Dec 2022 | premature ejaculation | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT05753098 | Jan 2021 → Jan 2023 | female infertility | Beni-Suef University | Completed | No outcome recorded |
| Phase 4 | NCT04325243 | Sep 2020 → Apr 2022 | — | Assiut University | Completed | No outcome recorded |
| Phase 4 | NCT03382106 | Mar 2018 → Sep 2024 | pulmonary emphysema | Eric A. Hoffman | Completed | No outcome recorded |
| Phase 4 | NCT02682147 | Jul 2017 → May 2025 overdue | pulmonary emphysema | Eric A. Hoffman | Active not recruiting | No outcome recorded |
| Phase 4 | NCT04908657 | Jul 2017 → Jul 2023 | fibrotic liver disease | National Taiwan University Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03044561 | Jan → Aug 2017 | infertility disorder | Ain Shams University | Unknown | No outcome recorded |
| Phase 4 | NCT02939495 | Oct 2016 → Jun 2017 | erectile dysfunction, premature ejaculation | Neutec Ar-Ge San ve Tic A.Ş | Completed | No outcome recorded |
| Phase 4 | NCT02524184 | Aug 2015 → Sep 2016 | obesity disorder | Xiang Guang-da | Unknown | No outcome recorded |
| Phase 4 | NCT02378649 | Mar 2015 → Jun 2018 | pulmonary hypertension | Dr. Robert Klempfner Heart Rehabilitation Institute | Completed | No outcome recorded |
| Phase 4 | NCT02620995 | Oct 2014 → Jan 2018 | erectile dysfunction, hypertensive disorder | National Institute of Cardiology, Laranjeiras, Brazil | Completed | No outcome recorded |
| Phase 4 | NCT02060487 | Sep 2014 → Feb 2021 | pulmonary arterial hypertension | Viatris Inc. | Terminated | No outcome recorded |
| Phase 4 | NCT02129725 | Apr 2014 → Oct 2016 | metabolic syndrome X | Vanderbilt University Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT03236818 | May 2013 → Sep 2017 | pulmonary arterial hypertension | Amsterdam UMC, location VUmc | Unknown | No outcome recorded |
| Phase 4 | NCT01889966 | Apr 2013 → Jan 2015 | pulmonary hypertension | Kerckhoff Heart Center | Completed | No outcome recorded |
| Phase 4 | NCT01800292 | Feb → Dec 2013 | left ventricular failure, pulmonary arterial hypertension | University of Arizona | Completed | No outcome recorded |
| Phase 4 | NCT01642407 | Aug 2012 → May 2016 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00730067 | Jun → Dec 2012 | chronic obstructive pulmonary disease, pulmonary hypertension | University of Aarhus | Withdrawn | No outcome recorded |
| Phase 4 | NCT01419392 | Sep 2011 → Apr 2012 | habitual spontaneous abortion | Ain Shams University | Unknown | No outcome recorded |
| Phase 4 | NCT01382368 | Sep 2011 → Nov 2012 | chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis | Rabin Medical Center | Unknown | No outcome recorded |
| Phase 4 | NCT01409993 | Aug 2011 → Nov 2016 | glucose intolerance | Vanderbilt University | Terminated | No outcome recorded |
| Phase 4 | NCT03733470 | Jun 2011 → Jan 2014 | pulmonary emphysema | Eric A. Hoffman | Completed | No outcome recorded |
| Phase 4 | NCT01352507 | Jun 2011 → Jun 2012 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 4 | NCT01060020 | Jan 2010 → Sep 2011 | aortic valve stenosis | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT00937144 | Sep 2009 | sickle cell disease | The Baruch Padeh Medical Center, Poriya | Withdrawn | No outcome recorded |
| Phase 4 | NCT01668446 | Sep 2009 | endometrial disorder | farzaneh hojjat | Completed | No outcome recorded |
| Phase 4 | NCT00862043 | Apr 2009 → Jul 2016 | heart valve disorder, pulmonary hypertension | Hospital General Universitario Gregorio Marañon | Completed | No outcome recorded |
| Phase 4 | NCT00793338 | Nov 2008 → Nov 2010 | congestive heart failure | University of New Mexico | Withdrawn | No outcome recorded |
| Phase 4 | NCT01055405 | Aug 2008 → Mar 2011 | chronic obstructive pulmonary disease, pulmonary hypertension | Hospital Clinic of Barcelona | Completed | No outcome recorded |
| Phase 4 | NCT00430716 | Apr 2008 → May 2010 | pulmonary arterial hypertension | Viatris Inc. | Terminated | No outcome recorded |
| Phase 4 | NCT00433329 | Mar 2007 → May 2010 | pulmonary arterial hypertension | Actelion | Completed | No outcome recorded |
| Phase 4 | NCT00625079 | Feb 2007 → Jun 2009 | idiopathic pulmonary fibrosis, pulmonary arterial hypertension | University of California, Los Angeles | Withdrawn | No outcome recorded |
| Phase 4 | NCT00781508 | Dec 2006 → Sep 2009 | left ventricular failure, symptomatic heart failure | MetroHealth Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00512707 | Nov 2006 → May 2010 | diabetes mellitus, erectile dysfunction, hypogonadism | Boston University | Completed | No outcome recorded |
| Phase 4 | NCT00323297 | Sep 2006 → Aug 2013 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00347867 | Jul 2006 → ? | fetal growth restriction | Rambam Health Care Campus | Unknown | No outcome recorded |
| Phase 4 | NCT00343200 | Jul 2006 → Sep 2007 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00350441 | Jun 2006 → ? | — | NHS Greater Glasgow Yorkhill Division | Unknown | No outcome recorded |
| Phase 4 | NCT00133679 | Feb 2006 → Jul 2013 | diaphragm disorder, pulmonary hypertension, pulmonary hypoplasia | University of California, San Francisco | Terminated | No outcome recorded |
| Phase 4 | NCT00455715 | Feb 2006 → Sep 2007 | schizophrenia | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00245258 | Nov 2005 → Sep 2006 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00301262 | Nov 2005 → Sep 2007 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00147628 | Nov 2005 → Sep 2006 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00249730 | Oct 2005 → ? | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00245596 | Oct 2005 → ? | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00313898 | Sep 2005 → Jun 2007 | erectile dysfunction | Rambam Health Care Campus | Unknown | No outcome recorded |
| Phase 4 | NCT00143260 | Aug 2005 → May 2006 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00159900 | May 2005 → Jan 2006 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00137072 | Apr 2005 → Feb 2006 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00150358 | Mar → Nov 2005 | erectile dysfunction, hypertensive disorder | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00151463 | Jan 2005 → ? | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00194909 | Aug 2004 → Jul 2006 | diabetic neuropathy | Weill Medical College of Cornell University | Completed | No outcome recorded |
| Phase 4 | NCT00194597 | Jul 2004 → Jul 2007 | prostatitis | University of Washington | Terminated | No outcome recorded |
| Phase 4 | NCT00159809 | Mar → Aug 2004 | depressive disorder, erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00143221 | Mar 2004 → May 2005 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00479908 | Jan 2004 → Sep 2005 | intermediate coronary syndrome | University of Edinburgh | Completed | No outcome recorded |
| Phase 4 | NCT01941732 | Nov 2003 → Feb 2004 | Parkinson disease, erectile dysfunction | Bispebjerg Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00483626 | Aug 2003 → Jun 2007 | pulmonary arterial hypertension | University of Chile | Unknown | No outcome recorded |
| Phase 4 | NCT00627965 | Mar 2003 → Feb 2008 | acute mountain sickness, high altitude pulmonary edema | Altitude Physiology Expeditions | Completed | No outcome recorded |
| Phase 4 | NCT00645268 | Dec 2002 → Jan 2004 | erectile dysfunction, type 2 diabetes mellitus | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00598585 | Jul 2002 → Dec 2010 | myalgic encephalomeyelitis/chronic fatigue syndrome | Charles Drew University of Medicine and Science | Completed | No outcome recorded |
| Phase 4 | NCT00145483 | Jun 2002 → Nov 2006 | Meniere disease | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00251784 | Feb 2002 → Jun 2003 | blindness (disorder) | University of Cambridge | Completed | No outcome recorded |
| Phase 4 | NCT00375297 | Jan 2001 → Jun 2005 | depressive disorder, sexual disorder | University of New Mexico | Completed | No outcome recorded |
| Phase not applicable31 trials | ||||||
| — | NCT04912726 | Jan 2025 → Jun 2026 | pulmonary hypertension, neonatal | Universidad del Norte | Withdrawn | No outcome recorded |
| — | NCT06237751 | Feb → Oct 2024 | — | First People's Hospital of Chenzhou | Unknown | No outcome recorded |
| — | NCT06562036 | Dec 2023 → May 2024 | pulmonary hypertension, neonatal | Muhammad Aamir Latif | Completed | No outcome recorded |
| — | NCT05889455 | Apr → Oct 2023 | migraine without aura | Danish Headache Center | Completed | No outcome recorded |
| — | NCT05669885 | Jan → Dec 2023 | traumatic encephalopathy | Danish Headache Center | Unknown | No outcome recorded |
| — | NCT05369481 | Mar → Aug 2022 | androgenetic alopecia | Mohammed Abd El Mawgoud Amer | Unknown | No outcome recorded |
| — | NCT04122105 | Apr 2021 → Jan 2023 | — | University of British Columbia | Withdrawn | No outcome recorded |
| — | NCT04344678 | Jan 2020 → Oct 2024 | major depressive disorder | Sadat City University | Withdrawn | No outcome recorded |
| — | NCT04170790 | Dec 2019 | erectile dysfunction, type 2 diabetes mellitus | Ain Shams University | Unknown | No outcome recorded |
| — | NCT04126252 | Aug 2018 → Sep 2019 | erectile dysfunction | International Islamic University, Islamabad | Completed | No outcome recorded |
| — | NCT03301233 | Nov 2017 → Jul 2018 | — | Ain Shams University | Completed | No outcome recorded |
| — | NCT03185364 | Jun 2017 → Dec 2020 | chronic obstructive pulmonary disease, pulmonary hypertension | Chinese Academy of Medical Sciences, Fuwai Hospital | Unknown | No outcome recorded |
| — | NCT03143465 | Aug 2016 → Dec 2018 | migraine with aura | Danish Headache Center | Unknown | No outcome recorded |
| — | NCT01572363 | Apr 2012 → Mar 2014 | congenital heart disease | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| — | NCT01548950 | Sep 2011 → Jan 2014 | congenital heart disease, pulmonary arterial hypertension | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| — | NCT01373749 | Mar → Dec 2011 | pulmonary hypertension, neonatal | Third Military Medical University | Unknown | No outcome recorded |
| — | NCT01812434 | Oct 2010 → Mar 2015 | — | University of Minnesota | Withdrawn | No outcome recorded |
| — | NCT01059994 | Jan 2010 → Jul 2013 | — | The University of Texas Medical Branch, Galveston | Completed | No outcome recorded |
| — | NCT00955929 | Aug 2009 → Dec 2020 | erectile dysfunction, penile cancer | Memorial Sloan Kettering Cancer Center | Terminated | No outcome recorded |
| — | NCT01948518 | Jun 2009 → Jun 2012 | interstitial lung disease, pulmonary hypertension | The Cleveland Clinic | Completed | No outcome recorded |
| — | NCT01391104 | Apr 2009 → Nov 2011 | pulmonary arterial hypertension | Laval University | Completed | No outcome recorded |
| — | NCT00772135 | Sep 2008 → Feb 2009 | congenital heart disease | Oslo University Hospital | Unknown | No outcome recorded |
| — | NCT00710099 | Jul 2008 → Jun 2011 | — | University Hospital, Grenoble | Completed | No outcome recorded |
| — | NCT00685945 | Dec 2007 → Jan 2009 | obesity disorder | Vanderbilt University | Completed | No outcome recorded |
| — | NCT00507286 | May 2007 → Sep 2008 | erectile dysfunction | Keogh Institute for Medical Research | Unknown | No outcome recorded |
| — | NCT00478335 | May 2007 → Oct 2012 | nephrogenic diabetes insipidus | University of Colorado, Denver | Completed | No outcome recorded |
| — | NCT00599235 | Mar 2007 → May 2008 | hypertensive disorder | University of Edinburgh | Completed | No outcome recorded |
| — | NCT00463957 | Aug 2006 → ? | erectile dysfunction | University of Cambridge | Unknown | No outcome recorded |
| — | NCT00297544 | Oct 2005 → ? | erectile dysfunction | Rambam Health Care Campus | Unknown | No outcome recorded |
| — | NCT00057759 | Jan 2003 → Dec 2006 | erectile dysfunction, prostate cancer, radiation-induced disorder | Radiation Therapy Oncology Group | Completed | No outcome recorded |
| — | NCT00155714 | Nov 2002 → May 2005 | pulmonary hypertension | National Taiwan University Hospital | Withdrawn | No outcome recorded |
| Phase not stated3 trials | ||||||
| — | NCT01897740 | — | pulmonary arterial hypertension | Viatris Inc. | No longer available | No outcome recorded |
| — | NCT00866983 | — | pulmonary arterial hypertension | Viatris Inc. | No longer available | No outcome recorded |
| — | NCT01582438 | — | pulmonary arterial hypertension | Viatris Inc. | No longer available | No outcome recorded |
Also used as a comparator or background therapy in 154 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 07 trials | ||||||
| Phase 0 | NCT06510322 Comparator | Mar 2025 → Dec 2029 expected | vascular disorder | Montefiore Medical Center | Recruiting | No outcome recorded |
| Phase 0 | NCT04770155 Comparator | May → Sep 2021 | vascular insufficiency disorder | University of Mississippi Medical Center | Terminated | No outcome recorded |
| Phase 0 | NCT03945643 Comparator | Jul 2019 → Jan 2023 | congenital arteriovenous fistula, patent foramen ovale | University of Oregon | Completed | No outcome recorded |
| Phase 0 | NCT03199612 Comparator | Jun 2019 → Jan 2023 | hemolytic anemia, thrombotic disease | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT03027674 Comparator | Aug 2016 | Raynaud disease, dermatomyositis, systemic lupus erythematosus, systemic sclerosis | Pontificia Universidad Catolica de Chile | Completed | No outcome recorded |
| Phase 0 | NCT04283240 Comparator | Mar 2015 → Sep 2017 | pulmonary embolism | University of Aarhus | Completed | No outcome recorded |
| Phase 0 | NCT00848497 Comparator | Nov 2007 → Mar 2013 | erectile dysfunction, hypogonadism | Mohit Khera | Terminated | No outcome recorded |
| Phase 117 trials | ||||||
| Phase 1 | NCT05765487 Comparator | May 2023 → Jan 2024 | sexual disorder | Daré Bioscience, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT06565728 Comparator | Nov 2022 → May 2023 | fetal growth restriction | Cairo University | Completed | No outcome recorded |
| Phase 1 | NCT03462017 Comparator | Mar → Dec 2018 | coronary microvascular disorder | Sanofi | Completed | No outcome recorded |
| Phase 1 | NCT03766594 Comparator | Jan → Nov 2018 | pregnancy loss, recurrent, 4 | Ain Shams University | Completed | No outcome recorded |
| Phase 1 | NCT02983461 Comparator | Mar 2017 → Mar 2020 overdue | — | The University of Texas Medical Branch, Galveston | Active not recruiting | No outcome recorded |
| Phase 1 | NCT03755037 Comparator | Jan 2017 → Apr 2018 | female infertility | Nesreen Abdel Fattah Abdullah Shehata | Completed | No outcome recorded |
| Phase 1 | NCT02812433 Comparator | Jul 2016 → Jan 2019 | — | McGill University Health Centre/Research Institute of the McGill University Health Centre | Completed | No outcome recorded |
| Phase 1 | NCT04391478 Comparator | Jan → Apr 2015 | pulmonary hypertension, neonatal | Rania Ali El-Farrash | Completed | No outcome recorded |
| Phase 1 | NCT02364882 Comparator | Jan → May 2015 | — | Strategic Science & Technologies, LLC | Completed | No outcome recorded |
| Phase 1 | NCT02337881 Comparator | Jan 2015 → Oct 2016 | — | Al Hayat National Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT02114775 Comparator | Dec 2014 → Nov 2017 | traumatic brain injury | The University of Texas Medical Branch, Galveston | Completed | No outcome recorded |
| Phase 1 | NCT02106871 Comparator | Apr 2014 → Jun 2017 | cholangiocarcinoma, malignant pancreatic neoplasm | The University of Texas Medical Branch, Galveston | Withdrawn | No outcome recorded |
| Phase 1 | NCT01409122 Background | Jul 2011 → Jan 2012 | pulmonary arterial hypertension | Aires Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01169519 Comparator | Apr 2011 → Dec 2012 | heart disorder | Duke University | Completed | No outcome recorded |
| Phase 1 | NCT00818701 Comparator | Feb 2009 → Aug 2010 | congestive heart failure, impaired renal function disease | Mayo Clinic | Terminated | No outcome recorded |
| Phase 1 | NCT00800592 Comparator | Oct → Dec 2008 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01616485 Comparator | Mar → May 2004 | erectile dysfunction | VIVUS LLC | Completed | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT06860399 Comparator | May 2023 → Sep 2024 | pulmonary hypertension, neonatal | Damascus University | Completed | No outcome recorded |
| Phase 1/2 | NCT04898114 Background | Jun 2021 → Apr 2025 overdue | pulmonary hypertension, neonatal | Sohag University | Recruiting | No outcome recorded |
| Phase 1/2 | NCT02595541 Comparator | Jun → Oct 2015 | pulmonary hypertension | Assiut University | Completed | No outcome recorded |
| Phase 1/2 | NCT00972569 Comparator | Oct 2009 → Jun 2019 | heart failure, impaired renal function disease | Mayo Clinic | Completed | No outcome recorded |
| Phase 225 trials | ||||||
| Phase 2 | NCT07231185 Comparator | Jan → Mar 2026 overdue | erectile dysfunction | Aspargo Labs, Inc | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06954597 Background | Feb 2025 → Oct 2026 expected | systemic sclerosis | Topadur Pharma AG | Recruiting | No outcome recorded |
| Phase 2 | NCT07135037 Comparator | Sep 2024 → Sep 2025 overdue | oligohydramnios | Kafrelsheikh University | Recruiting | No outcome recorded |
| Phase 2 | NCT05782244 Comparator | Jul 2024 → Dec 2027 expected | traumatic brain injury | University of Pennsylvania | Recruiting | No outcome recorded |
| Phase 2 | NCT06098833 Comparator | Jul 2024 → Oct 2027 expected | — | Pia Wintermark | Recruiting | No outcome recorded |
| Phase 2 | NCT05556083 Comparator | Oct 2022 → Sep 2023 | premature ejaculation | Al-Azhar University | Unknown | No outcome recorded |
| Phase 2 | NCT05201144 Comparator | Sep 2022 → Mar 2026 overdue | congenital diaphragmatic hernia, pulmonary hypertension | University of Utah | Recruiting | No outcome recorded |
| Phase 2 | NCT04447989 Comparator | May 2021 → Dec 2024 | bronchopulmonary dysplasia | Christoph Hornik | Completed | No outcome recorded |
| Phase 2 | NCT03686813 Comparator | Jul 2019 → Oct 2021 | pulmonary edema | Duke University | Completed | No outcome recorded |
| Phase 2 | NCT03598140 Comparator | Jul 2018 → May 2019 | traumatic encephalopathy, vascular brain injury | University of Texas Southwestern Medical Center | Terminated | No outcome recorded |
| Phase 2 | NCT02678221 Comparator | Feb 2016 → Feb 2017 | fetal growth restriction | Assiut University | Unknown | No outcome recorded |
| Phase 2 | NCT02845388 Comparator | Sep 2015 → May 2016 | infertility disorder | Omar Ahmed El Sayed Saad | Completed | No outcome recorded |
| Phase 2 | NCT02390960 Comparator | Mar 2015 → Apr 2017 | erectile dysfunction | Strategic Science & Technologies, LLC | Completed | No outcome recorded |
| Phase 2 | NCT02422277 Comparator | Mar 2015 → Mar 2017 | urinary bladder cancer | Mansoura University | Unknown | No outcome recorded |
| Phase 2 | NCT04356716 Comparator | Nov 2014 → Feb 2020 | age-related macular degeneration, central serous chorioretinopathy, optic choroid disorder, retinitis pigmentosa +1 | Columbia University | Completed | No outcome recorded |
| Phase 2 | NCT01517854 Comparator | Nov 2012 → Oct 2017 | pulmonary arterial hypertension | University Health Network, Toronto | Terminated | No outcome recorded |
| Phase 2 | NCT01179334 Background | Aug 2010 → Jun 2012 | pulmonary hypertension | Bayer | Completed | No outcome recorded |
| Phase 2 | NCT00853112 Comparator | Apr 2009 → Jul 2010 | pulmonary arterial hypertension | Pfizer | Terminated | No outcome recorded |
| Phase 2 | NCT01185925 Comparator | Apr 2008 → Dec 2009 | heart failure | University of Milan | Completed | No outcome recorded |
| Phase 2 | NCT00507819 Comparator | Dec 2007 → Apr 2009 | hypoplastic left heart syndrome, tricuspid atresia | Children's Hospital of Philadelphia | Completed | No outcome recorded |
| Phase 2 | NCT00862888 Comparator | Jul 2007 → Feb 2008 | erectile dysfunction | Pfizer | Completed | No outcome recorded |
| Phase 2 | NCT00334490 Comparator | Mar 2005 → Apr 2009 | pulmonary hypertension | Unity Health Toronto | Completed | No outcome recorded |
| Phase 2 | NCT00104637 Comparator | Feb 2005 → Nov 2008 | pulmonary emphysema | Kawut, Steven, MD | Completed | No outcome recorded |
| Phase 2 | NCT00645034 Comparator | Nov 2002 → Jul 2003 | benign prostatic hyperplasia | Viatris Inc. | Completed | No outcome recorded |
| Phase 2 | NCT00080808 Comparator | Aug 2001 → Jul 2006 | prostate cancer | M.D. Anderson Cancer Center | Completed | No outcome recorded |
| Phase 2/310 trials | ||||||
| Phase 2/3 | NCT04039087 Comparator | Sep 2019 → Jun 2024 | cystic fibrosis | National Jewish Health | Completed | No outcome recorded |
| Phase 2/3 | NCT02442492 Comparator | Jan 2017 → Jul 2018 | fetal growth restriction | University of British Columbia | Terminated | No outcome recorded |
| Phase 2/3 | NCT03262961 Comparator | Sep 2016 → Dec 2017 | mild pre-eclampsia | Assiut University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02798159 Comparator | May 2016 → Mar 2018 | erectile dysfunction | Vietstar Biomedical Research | Completed | No outcome recorded |
| Phase 2/3 | NCT02387450 Comparator | Sep 2015 → Jun 2017 | peripheral arterial disease | University Hospital, Angers | Unknown | No outcome recorded |
| Phase 2/3 | NCT02277132 Comparator | Jan 2015 → Jul 2018 | fetal growth restriction | Academic Medical Center - University of Amsterdam | Terminated | No outcome recorded |
| Phase 2/3 | NCT01637675 Background | May 2013 → Dec 2014 | lung disorder, pulmonary arterial hypertension | The First Affiliated Hospital of Guangzhou Medical University | Unknown | No outcome recorded |
| Phase 2/3 | NCT00872170 Comparator | Mar 2009 → Jun 2010 | pulmonary hypertension, thalassemia | Carelon Research | Completed | No outcome recorded |
| Phase 2/3 | NCT00752115 Comparator | Feb 2007 → Mar 2009 | non-small cell lung carcinoma | Hamamatsu University | Completed | No outcome recorded |
| Phase 2/3 | NCT01156636 Comparator | Jan 2006 → Sep 2009 | diastolic heart failure, pulmonary hypertension | University of Milan | Completed | No outcome recorded |
| Phase 328 trials | ||||||
| Phase 3 | NCT07177326 Comparator | Oct 2025 → Oct 2026 expected | erectile dysfunction | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT06123156 Comparator | Sep 2025 → Feb 2030 expected | rectal cancer | University Hospital, Rouen | Recruiting | No outcome recorded |
| Phase 3 | NCT06377098 Comparator | May 2025 → Aug 2026 | perinatal asphyxia | University of Alabama at Birmingham | Withdrawn | No outcome recorded |
| Phase 3 | NCT06522854 Comparator | May 2025 → May 2026 | perinatal asphyxia | University of Alabama at Birmingham | Withdrawn | No outcome recorded |
| Phase 3 | NCT04039464 Comparator | Aug 2022 → Dec 2025 | pulmonary arterial hypertension | Johns Hopkins University | Completed | No outcome recorded |
| Phase 3 | NCT05584956 Comparator | Jul 2022 → Jul 2023 | beta thalassemia | Tanta University | Unknown | No outcome recorded |
| Phase 3 | NCT03460470 Comparator | Feb → Dec 2018 | heart failure, pulmonary hypertension | Hartford Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT03406169 Comparator | Feb 2017 → Dec 2021 | erectile dysfunction, prostate cancer | Brooke Army Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT02802345 Comparator | Jun 2016 → Dec 2017 | idiopathic pulmonary fibrosis | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase 3 | NCT01616381 Comparator | Mar 2013 → Jun 2018 | heart failure, pulmonary hypertension | Helse Stavanger HF | Unknown | No outcome recorded |
| Phase 3 | NCT01558466 Comparator | Nov 2011 → Nov 2014 | persistent fetal circulation syndrome | Hamad Medical Corporation | Unknown | No outcome recorded |
| Phase 3 | NCT01726049 Comparator | Oct 2011 → Sep 2014 | diastolic heart failure, pulmonary hypertension | University Medical Center Groningen | Completed | No outcome recorded |
| Phase 3 | NCT01321489 Comparator | Sep 2011 → Jan 2012 | erectile dysfunction | Laboratório Teuto Brasileiro S/A | Unknown | No outcome recorded |
| Phase 3 | NCT01347008 Comparator | Apr 2011 → Jan 2013 | Raynaud disease, diffuse scleroderma, limited systemic sclerosis | Federal University of São Paulo | Completed | No outcome recorded |
| Phase 3 | NCT01315262 Comparator | Jan 2011 → Sep 2012 | erectile dysfunction | Vita-Salute San Raffaele University | Unknown | No outcome recorded |
| Phase 3 | NCT01295736 Comparator | Nov 2010 → Aug 2013 | systemic sclerosis | University Hospital, Lille | Completed | No outcome recorded |
| Phase 3 | NCT01441934 Comparator | Oct 2010 → Feb 2013 | chronic obstructive pulmonary disease, pulmonary hypertension | Italian Association of Hospital Pneumologists | Unknown | No outcome recorded |
| Phase 3 | NCT01063855 Background | Apr 2010 → Aug 2011 | erectile dysfunction, sexual disorder | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Completed | No outcome recorded |
| Phase 3 | NCT00586794 Comparator | Dec 2007 → May 2012 | pulmonary arterial hypertension | Competence Network for Congenital Heart Defects | Terminated | No outcome recorded |
| Phase 3 | NCT00517933 Comparator | Aug 2007 → May 2009 | idiopathic pulmonary fibrosis, pulmonary hypertension | Duke University | Completed | No outcome recorded |
| Phase 3 | NCT00454714 Comparator | Mar 2007 → Dec 2009 | coronary vasospasm | Udo Sechtem | Withdrawn | No outcome recorded |
| Phase 3 | NCT00431418 Comparator | Jan 2007 → Jul 2010 | lung disorder | Mercy Hospital for Women, Australia | Completed | No outcome recorded |
| Phase 3 | NCT00302211 Background | Feb 2006 → Dec 2007 | pulmonary hypertension | Actelion | Terminated | No outcome recorded |
| Phase 3 | NCT00975494 Comparator | Apr 2005 → Dec 2008 | heart failure | University of Milan | Completed | No outcome recorded |
| Phase 3 | NCT00142506 Comparator | Feb 2005 → Apr 2014 | erectile dysfunction, prostate cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 3 | NCT00547287 Comparator | Nov 2002 → May 2004 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 3 | NCT00644605 Comparator | Oct 2002 → Nov 2003 | pulmonary arterial hypertension | Viatris Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00780728 Comparator | — | pulmonary arterial hypertension | University Health Network, Toronto | Withdrawn | No outcome recorded |
| Phase 443 trials | ||||||
| Phase 4 | NCT07713914 Comparator | Jul 2026 → Jul 2028 expected | pulmonary arterial hypertension | University of Sao Paulo General Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07391579 Comparator | Dec 2025 → Dec 2026 expected | erectile dysfunction | Mansoura University | Recruiting | No outcome recorded |
| Phase 4 | NCT06649539 Background | Oct 2024 → Oct 2029 expected | Peyronie disease | Charitable Union for the Research and Education of Peyronie's Disease | Recruiting | No outcome recorded |
| Phase 4 | NCT06178523 Comparator | Jan → Dec 2024 | infertility disorder | Batterjee Medical College | Completed | No outcome recorded |
| Phase 4 | NCT06317805 Background | Dec 2023 → Jun 2027 expected | pulmonary arterial hypertension | AOP Orphan Pharmaceuticals AG | Recruiting | No outcome recorded |
| Phase 4 | NCT05558176 Comparator | Apr → Oct 2022 | perinatal asphyxia | Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso | Unknown | No outcome recorded |
| Phase 4 | NCT04538976 Comparator | Feb 2020 → Mar 2024 | — | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | Completed | No outcome recorded |
| Phase 4 | NCT06064448 Comparator | Mar 2019 → Dec 2022 | chronic prostatitis, erectile dysfunction | Xintian Pharmaceutical | Completed | No outcome recorded |
| Phase 4 | NCT03633565 Comparator | Sep 2018 → Sep 2021 | myopathy | Assiut University | Unknown | No outcome recorded |
| Phase 4 | NCT03431649 Comparator | Apr → Jul 2017 | pulmonary hypertension | Dr. Soetomo General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02891850 Comparator | Jan 2017 → Jan 2020 | pulmonary arterial hypertension | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT03053739 Comparator | Dec 2016 → Dec 2017 | pulmonary arterial hypertension | Post Graduate Institute of Medical Education and Research, Chandigarh | Unknown | No outcome recorded |
| Phase 4 | NCT02890238 Comparator | Aug 2016 → Oct 2019 | female infertility | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT03402191 Comparator | Jul 2016 → Dec 2023 | thalassemia | Tanta University | Unknown | No outcome recorded |
| Phase 4 | NCT03169582 Comparator | Apr 2016 → Jun 2018 | erectile dysfunction | Eduardo Vargas-Baquero | Unknown | No outcome recorded |
| Phase 4 | NCT02304705 Comparator | Jan 2015 → Jun 2017 | pulmonary hypertension | Maya Guglin | Terminated | No outcome recorded |
| Phase 4 | NCT02284737 Background | Nov 2014 → Jul 2021 | pulmonary arterial hypertension | Nanjing First Hospital, Nanjing Medical University | Terminated | No outcome recorded |
| Phase 4 | NCT02519153 Comparator | Jul 2014 → Aug 2017 | ureterolithiasis, urolithiasis | Mansoura University | Unknown | No outcome recorded |
| Phase 4 | NCT02345980 Comparator | Mar 2014 → Nov 2016 | — | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT01757782 Comparator | Dec 2011 → Aug 2012 | meconium aspiration syndrome, pulmonary hypertension, neonatal | Sir Takhtasinhji General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01449253 Comparator | Aug 2011 → Jul 2013 | pulmonary hypertension owing to lung disease and/or hypoxia | All India Institute of Medical Sciences | Unknown | No outcome recorded |
| Phase 4 | NCT01364701 Comparator | Jun 2011 → Jun 2012 | erectile dysfunction | Rambam Health Care Campus | Unknown | No outcome recorded |
| Phase 4 | NCT01122264 Comparator | May 2010 → Jun 2011 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 4 | NCT01046838 Comparator | Dec 2009 → Mar 2012 | diastolic heart failure | Jacob E Mueller | Completed | No outcome recorded |
| Phase 4 | NCT00964782 Comparator | Aug 2009 → May 2012 | congenital cardiovascular shunt | Milton S. Hershey Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00906269 Comparator | Jul 2009 → Jul 2020 | erectile dysfunction, prostate neoplasm | Hartford Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT00902512 Comparator | Apr 2009 | — | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00617305 Background | Apr 2008 → Feb 2011 | pulmonary arterial hypertension | Gilead Sciences | Completed | No outcome recorded |
| Phase 4 | NCT00692237 Comparator | Jan 2008 → Sep 2009 | type 2 diabetes mellitus | University of Roma La Sapienza | Completed | No outcome recorded |
| Phase 4 | NCT00491803 Comparator | Jun 2007 → Nov 2008 | chronic obstructive pulmonary disease, pulmonary hypertension | Hospital Clinic of Barcelona | Completed | No outcome recorded |
| Phase 4 | NCT00468650 Comparator | Jun 2007 → Feb 2008 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00498680 Comparator | Mar 2007 → Jan 2011 | erectile dysfunction | Rambam Health Care Campus | Unknown | No outcome recorded |
| Phase 4 | NCT00461565 Comparator | Feb 2005 → Oct 2006 | — | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT00655590 Comparator | Jan 2005 → Jun 2006 | erectile dysfunction | Bayer | Completed | No outcome recorded |
| Phase 4 | NCT00199563 Comparator | Aug 2004 → Oct 2007 | erectile dysfunction | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Completed | No outcome recorded |
| Phase 4 | NCT00547352 Comparator | Jun 2004 → Jun 2005 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 4 | NCT00547092 Comparator | Oct 2003 → Nov 2004 | erectile dysfunction | Eli Lilly and Company | Completed | No outcome recorded |
| Phase 4 | NCT00644956 Comparator | Jun → Nov 2003 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00644631 Comparator | Jun 2003 → Apr 2004 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00648596 Comparator | May 2003 → May 2004 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00654017 Comparator | Oct 2002 → Apr 2005 | erectile dysfunction | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT00654082 Comparator | Sep 2002 → Aug 2003 | erectile dysfunction, spinal cord injury | Viatris Inc. | Completed | No outcome recorded |
| Phase 4 | NCT01153204 Comparator | — | erectile dysfunction | Federal University of São Paulo | Completed | No outcome recorded |
| Phase not applicable19 trials | ||||||
| — | NCT07293156 Background | Dec 2025 → Jun 2026 | diabetes mellitus, erectile dysfunction | Benha University | Completed | No outcome recorded |
| — | NCT07057011 Comparator | Jul 2025 → Feb 2026 overdue | premature ejaculation | South Valley University | Not yet recruiting | No outcome recorded |
| — | NCT06778330 Comparator | Jan → Aug 2025 | moderate heart failure | Fayoum University | Completed | No outcome recorded |
| — | NCT05741229 Comparator | Jan → Dec 2024 | pulmonary hypertension, neonatal, respiratory system disorder | Alexandria University | Completed | No outcome recorded |
| — | NCT03854175 Comparator | Feb 2019 → Jan 2020 | infertility disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT03724838 Comparator | Dec 2018 → Nov 2021 | preeclampsia | Aswan University Hospital | Unknown | No outcome recorded |
| — | NCT04179747 Comparator | Jan → Jul 2018 | erectile dysfunction | International Islamic University, Islamabad | Completed | No outcome recorded |
| — | NCT03475160 Comparator | Dec 2015 → Dec 2017 | habitual spontaneous abortion | Benha University | Completed | No outcome recorded |
| — | NCT03710369 Comparator | Nov 2015 → Oct 2018 | — | University of British Columbia | Completed | No outcome recorded |
| — | NCT02414204 Comparator | Apr 2015 → Jun 2017 | — | University of Alabama at Birmingham | Completed | No outcome recorded |
| — | NCT02362399 Comparator | Mar 2015 → Apr 2016 | obstetric disorder | Al Hayat National Hospital | Completed | No outcome recorded |
| — | NCT02372487 Comparator | Mar 2015 → Jun 2016 | pregnancy disorder | Al Hayat National Hospital | Unknown | No outcome recorded |
| — | NCT01996852 Background | Jul 2013 → Aug 2016 | erectile dysfunction, prostate cancer | Case Comprehensive Cancer Center | Terminated | No outcome recorded |
| — | NCT01661595 Comparator | Nov 2012 → Jun 2015 | — | The University of Texas Medical Branch, Galveston | Completed | No outcome recorded |
| — | NCT01392638 Comparator | Jul 2010 → Jul 2012 | hypertensive disorder | University of Campinas, Brazil | Completed | No outcome recorded |
| — | NCT01054001 Comparator | Jun 2010 → Dec 2012 | prostate cancer | Seoul National University Bundang Hospital | Unknown | No outcome recorded |
| — | NCT01044693 Comparator | Jan 2010 → Jul 2014 | hypertensive disorder, pure autonomic failure | Vanderbilt University | Completed | No outcome recorded |
| — | NCT00808912 Comparator | Dec 2008 → Feb 2010 | pulmonary hypertension | Marywood University | Completed | No outcome recorded |
| — | NCT00511498 Comparator | Mar 2006 → Sep 2007 | prostate cancer | Johns Hopkins University | Completed | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT00878943 Background | — | pulmonary arterial hypertension | Viatris Inc. | No longer available | No outcome recorded |
Press releases naming this drug 6 releases
| Date | Issuer | Release |
|---|---|---|
| 2020-01-23 | Pfizer | Pfizer’s Greenstone and Digital Men’s Health Clinic Roman Collaborate to Offer Patients Remote Access to the Only FDA-Approved Authorized Generic Version of Viagra® (sildenafil citrate) pfizer.com ↗ |
| 2019-06-28 | Pfizer | Pfizer Announces Results from Phase 3 Trial of Revatio® (Sildenafil Citrate) in Newborns with Persistent Pulmonary Hypertension pfizer.com ↗ |
| 2017-12-11 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Announces Exclusive Launch of a Generic Version Viagra® Tablets in the United States tevapharm.com ↗ |
| 2013-12-17 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Settles Viagra® Patent Litigation with Pfizer tevapharm.com ↗ |
| 2013-06-24 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Launches Generic Version of Viagra® (sildenafil) in Countries Across Europe tevapharm.com ↗ |
| 2007-08-10 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Announces Tentative Approval Of Sildenafil Citrate Tablets, 20 Mg tevapharm.com ↗ |
Evidence & citations 22 cited values
Every value below carries the sentence it was read from. 425 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | sildenafil | “Patients were to be using a stable regimen of a PDE5-I (i.e., sildenafil, vardenafil, or tadalafil), as reported by the patient for the treatment of erectile dysfunction (ED)...” NCT01063855 ↗372“All patients will receive standard of care double oral background treatment consisting of one Phosphodiesterase type 5 inhibitor (i.e., tadalafil or sildenafil) and one...” NCT06317805 ↗ “This is a single dose open-label comparative pharmacokinetic study to assess the pharmacokinetic characteristics of sildenafil between HIP0908 (chewable tablet) and Viagra...” NCT01514903 ↗ “A Phase 1 Pharmacokinetic/Bioequivalence Study of 100 Mg of HEZKUE® (ASP-001, Sildenafil) Versus 100 Mg of VIAGRA® (Sildenafil) Film-Coated Tablets Under Fasted Conditions in...” NCT06782659 ↗ “The objective of this study was to evaluate the effects of a triple combination of leucine, metformin, and sildenafil (NS-0200) on body weight and obesity comorbidities in a...” PMID 30569637 ↗ Jan 2019 “patients will receive sildenafil which is used routinely in management of PPHN in our unit, in addition to appropriate oxygenation and ventilation.” NCT05741229 ↗ “Sildenafil is efficacious in newborns with persistent pulmonary hypertension and its use will reduce the need for inhaled nitric oxide.” NCT01069861 ↗ “The PDE-5 inhibitor, sildenafil, is approved for use in patients with PAH and commonly used in the initial treatment for PAH.” NCT01409122 ↗ “Sildenafil (REVATIO®) was approved for the treatment of adult Pulmonary Arterial Hypertension (PAH) in the US and the EU.” PMID 31538282 ↗ Sep 2019 “two fixed-dose combinations of leucine and sildenafil or two fixed-dose combinations of leucine, sildenafil and metformin” NCT03364335 ↗ “Sildenafil is an effective treatment for male penile erectile dysfunction that inhibits the breakdown cGMP.” NCT00479908 ↗ “The purpose of this study is to evaluate pharmacokinetics of sildenafil citrate in healthy male volunteers.” NCT01651858 ↗ “all enrolled subjects will be up titrated to sildenafil 100 mg PRN for the following four weeks.” NCT00468650 ↗ “An orally disintegrating film (ODF) formulation of sildenafil was recently developed in Korea.” NCT01769638 ↗ “Ro Sparks® is a combination sildenafil + tadalafil product administered on an on-demand basis.” NCT07231185 ↗ “Using Oral Sildenafil and Intracavernosal Alprostadil Injection as a Combined Pharmacotherapy” NCT00507286 ↗ “combination BNP/PDEV inhibition with sildenafil (25 mg q12 hours) for 48 hours” PMID 39513267 ↗ Nov 2024 “SST-6007 is a white to off-white cream containing 5% (w/w) sildenafil citrate” NCT02570282 ↗ “Three Orally Disintegrating Tablet Formulations Of Sildenafil Without Water” NCT00950404 ↗ “Study Of Bioavailability Of Two Sildenafil 100mg Oral Tablet Formulations” NCT00902512 ↗ “Contains chlomipramine HCl 15mg and sildenafil citrate 25mg.” NCT02571101 ↗ “single oral administration of 100mg sildenafil” NCT00767598 ↗ “Sildenafil citrate 100mg (Viagra Tab)” NCT02028598 ↗ “Oral liquid suspension of sildenafil” NCT07117383 ↗ “sildenafil 25mg Oral Tablet” NCT07057011 ↗ |
| Known as | ASP-001 | “A Phase 1 Pharmacokinetic/Bioequivalence Study of 100 Mg of HEZKUE® (ASP-001, Sildenafil) Versus 100 Mg of VIAGRA® (Sildenafil) Film-Coated Tablets Under Fasted Conditions in...” NCT06782659 ↗ |
| Known as | Bilayer Matrix Wound Dressing | “Another ADM product available in the market is made by Integra® (Bilayer Matrix Wound Dressing, Integra LifeSciences).” NCT03476876 ↗ |
| Known as | Hezkue | “Hezkue® oral sildenafil suspension will be administered as a single oral dose following controlled moderate alcohol consumption under fasting or standardized conditions,...” NCT07302698 ↗2“A Phase 1 Pharmacokinetic/Bioequivalence Study of 100 Mg of HEZKUE® (ASP-001, Sildenafil) Versus 100 Mg of VIAGRA® (Sildenafil) Film-Coated Tablets Under Fasted Conditions in...” NCT06782659 ↗ “Hezkue® sildenafil oral suspension will be administered as a single oral dose in each study period under different alcohol intake conditions” NCT07290400 ↗ |
| Known as | Integra | “Another ADM product available in the market is made by Integra® (Bilayer Matrix Wound Dressing, Integra LifeSciences).” NCT03476876 ↗ |
| Known as | PDE-5 inhibitors group | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02422277 ↗ |
| Known as | Pfizer Viagra | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07231185 ↗ |
| Known as | Respatio | “Sildenafil citrate (trade name: Revatio, Viagra, Respatio, etc.) was emerged as a drug helping vasodilation” NCT06565728 ↗ |
| Known as | Respatio(R) | “Includes 45 women who received Sildenafil citrate (Respatio(R) 25mg tablets four times daily for 24 days preconceptionally starting first day of previous period) and folic acid...” NCT03766594 ↗ |
| Known as | Revatio | “Sildenafil, commonly known as Revatio or Viagra, is a medication that increases the supply of blood to the lungs and reduces the workload of the heart.” NCT00763867 ↗8“Sildenafil (REVATIO®) was approved for the treatment of adult Pulmonary Arterial Hypertension (PAH) in the US and the EU.” PMID 31538282 ↗ Sep 2019 “Effects of Sildenafil Citrate (Revatio) 20 mg TID on Patients With Portal Pulmonary Arterial Hypertension (PPAH)” NCT01517854 ↗ “Sildenafil citrate (trade name: Revatio, Viagra, Respatio, etc.) was emerged as a drug helping vasodilation” NCT06565728 ↗ “the drug sildenafil (Revatio®) can improve muscular, cardiac, cerebrovascular or cognitive function” NCT01350154 ↗ “Sildenafil (Revatio®) an inhibitor of the phosphodiesterase 5 (PDE-5)” NCT00586794 ↗ “Active Drug: Sildenafil tablets (Revatio)” NCT02335242 ↗ “sildenafil (Revatio) 20 mg TID” NCT00866983 ↗ |
| Known as | Revation | “Sildenafil (Revation) 20 mg” NCT01350154 ↗ |
| Known as | silden | “sildenafil (silden® 25, E.I.P.I.CO.)” NCT03301233 ↗ |
| Known as | Sildenafil citrate | “A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled, Flexible Dose Escalation Study To Evaluate Sexual And Relationship Satisfaction In The Female...” NCT00644631 ↗86“A Prospective Multicenter, Parallel Group Study With A Single Blind Phase And A Double Blind Randomised Phase, To Evaluate The Efficacy And Satisfaction Of Viagra (Sildenafil...” NCT00249730 ↗ “A Randomized, Open-Label, Crossover, Multicenter, Single Dose Comparator Study Evaluating Onset Of Penile Rigidity In Men With Erectile Dysfunction Who Are Treated With Viagra...” NCT00644956 ↗ “Viagra (Sildenafil citrate) is an orally active selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) which is used for the...” NCT01315262 ↗ “A Multicenter, Double-blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Viagra® (Sildenafil Citrate) on the PRN Efficacy of Viagra in Men With Erectile...” NCT00645268 ↗ “An Open Label, Multicenter Study to Measure Treatment Responsiveness of Quality of Sexual Life Questionnaire in the Female Partner of Men With Erectile Dysfunction Treated With...” NCT00245596 ↗ “An Open-Label, Non-Comparative Study To Evaluate Treatment Responsiveness To The Quality Of Erection Questionnaire (QEQ) In Men With Erectile Dysfunction Treated With Viagra...” NCT00151463 ↗ “One hour before each study part, a pharmacy produced capsule (envelope coded and drawn in a random manner from a box) containing either sildenafil citrate 50 mg or placebo will...” NCT00772135 ↗ “Sildenafil citrate is a phosphodiesterase-5 (PDE-5) inhibitor that is FDA-approved and widely used as a therapy for primary pulmonary hypertension and erectile dysfunction.” NCT05782244 ↗ “The phosphodiesterase 5 inhibitor, sildenafil citrate, slightly reduces systolic and diastolic blood pressures in treated hypertensives patients.” NCT01392638 ↗ “Among premature infants with severe BPD, enteral sildenafil citrate did not increase the incidence of hypotension or retinopathy of prematurity.” PMID 42105936 ↗ May 2026 “Efficacy of Sildenafil Citrate to Reduce the Rate of Cesarean Section for Intrapartum Fetal Distress During Induction of Labor” NCT04325243 ↗ “sildenafil citrate 25 mg every 8 hours (Silden EIPICO co.) orally, starting at the diagnosis of FGR till delivery” NCT03230162 ↗ “Effects of Sildenafil Citrate (Revatio) 20 mg TID on Patients With Portal Pulmonary Arterial Hypertension (PPAH)” NCT01517854 ↗ “Each participant will receive, after informed consent a 25 mg tablet of Viagra \[sildenafil citrate \]orally.” NCT00347867 ↗ “Sildenafil citrate (trade name: Revatio, Viagra, Respatio, etc.) was emerged as a drug helping vasodilation” NCT06565728 ↗ “Sildenafil citrate at a dose of 25mg will be administered orally in patients with recurrent pregnancy loss” NCT04718233 ↗ “Subjects were given sildenafil citrate, 25mg/capsule, once a night, one capsule each time, for 4 weeks.” NCT06064448 ↗ “sildenafil citrate (Respatio) 20 mg tab orally 3 times daily from8th day of same cycle till 11th day” NCT03755037 ↗ “Sildenafil Citrate (Viagra®), a vasodilator, is also described as an anti-inflammatory agent.” NCT03766594 ↗ “oral 50 mg. tablets of Sildenafil Citrate in an on demand open label, flexible dose fashion.” NCT00142506 ↗ “Sildenafil citrate (Viagra) has proved effective for erectile dysfunction in many men.” PMID 10524880 ↗ Nov 1999 “Sildenafil citrate is indicated for the treatment of erectile dysfunction.” PMID 24447534 ↗ Jan 2014 “50mg sildenafil citrate/tablet, crushed in water taken by nasogastric tube” NCT04391478 ↗ “with a PDE-5 inhibitor (sildenafil citrate) will improve pre-diabetes” NCT01334554 ↗ “randomly assigned to sildenafil citrate or placebo” PMID 19843000 ↗ Aug 2009 “Sildenafil Citrate 40 mg t.i.d. oral” NCT00862043 ↗ “Viagra (Sildenafil Citrate) 100 mg” NCT00143260 ↗ “Viagra (Sildenafil Citrate) 100 mg” NCT00137072 ↗ “sildenafil citrate (UK-92,480)” NCT00454207 ↗ “Viagra (Sildenafil citrate)” NCT00159809 ↗ “Viagra (sildenafil citrate)” NCT00194597 ↗ “Sildenafil citrate (Viagra)” NCT00165295 ↗ “Viagra (Sildenafil Citrate)” NCT00143221 ↗ “Sildenafil Citrate 50Mg Tab” NCT04126252 ↗ “Sildenafil Citrate 25Mg Tab” NCT03177824 ↗ “Viagra (Sildenafil citrate)” NCT00301262 ↗ “Drug: Sildenafil Citrate” NCT05061368 ↗ “Drug: Sildenafil Citrate” NCT03598140 ↗ “Drug: Sildenafil Citrate” NCT02466802 ↗ “Drug: Sildenafil Citrate” NCT00323297 ↗ “Drug: Sildenafil citrate” NCT01441934 ↗ “Drug: Sildenafil citrate” NCT01419392 ↗ “Drug: Sildenafil citrate” NCT00430716 ↗ “Drug: Sildenafil citrate” NCT00159913 ↗ “Drug: Sildenafil Citrate” NCT04565925 ↗ “Drug: Sildenafil Citrate” NCT05951413 ↗ “Drug: Sildenafil Citrate” NCT03356353 ↗ “Sildenafil Citrate” NCT03475160 ↗ |
| Known as | Sildenafil Citrate 20 mg ( Respatio 20 mg) | “Sildenafil Citrate 20 mg ( Respatio® 20 mg)” NCT03262961 ↗ |
| Known as | SST-6006 | “5% Sildenafil Cream (SST-6006)” NCT01986673 ↗ |
| Known as | SST-6007 | “SST-6007 is a white to off-white cream containing 5% (w/w) sildenafil citrate” NCT02570282 ↗ |
| Known as | UK-92,480 | “sildenafil citrate (UK-92,480)” NCT00454207 ↗ |
| Known as | Viagra | “The same brand of sildenafil citrate (VIAGRA, manufactured by Fareva Amboise Zone Industrielle, 29 route des Industries, 37530 Poce Sur Cisse, France, under authority of Pfizer...” NCT05558176 ↗48“A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled, Flexible Dose Escalation Study To Evaluate Sexual And Relationship Satisfaction In The Female...” NCT00644631 ↗ “A Randomized, Open-Label, Crossover, Multicenter, Single Dose Comparator Study Evaluating Onset Of Penile Rigidity In Men With Erectile Dysfunction Who Are Treated With Viagra...” NCT00644956 ↗ “Viagra (Sildenafil citrate) is an orally active selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) which is used for the...” NCT01315262 ↗ “Does pre-operative administration of Sildenafil (Viagra, Pfizer) reduce the lung injury associated with cardiopulmonary bypass in children undergoing corrective surgical repair...” NCT00350441 ↗ “A Multicenter, Double-blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Viagra® (Sildenafil Citrate) on the PRN Efficacy of Viagra in Men With Erectile...” NCT00645268 ↗ “An Open Label, Multicenter Study to Measure Treatment Responsiveness of Quality of Sexual Life Questionnaire in the Female Partner of Men With Erectile Dysfunction Treated With...” NCT00245596 ↗ “A Phase 1 Pharmacokinetic/Bioequivalence Study of 100 Mg of HEZKUE® (ASP-001, Sildenafil) Versus 100 Mg of VIAGRA® (Sildenafil) Film-Coated Tablets Under Fasted Conditions in...” NCT06782659 ↗ “An Open-Label, Non-Comparative Study To Evaluate Treatment Responsiveness To The Quality Of Erection Questionnaire (QEQ) In Men With Erectile Dysfunction Treated With Viagra...” NCT00151463 ↗ “In 40 of the 80 subjects during the smoking cessation program, we will provide three times per day Sildenafil 20 milligrams (MG) (Viagra) for the full 3 months of the smoking...” NCT03382106 ↗ “To compare the efficacy and safety of Viagra (sildenafil citrate) vs. placebo for the treatment of men with ED and at least 1 prespecified risk factor who do not self identify...” NCT00343200 ↗ “Three studies have evaluated PDE-5 inhibitors in patients with erectile dysfunction after rectal resection, two of which used sildenafil (Viagra, Pfizer, New York, NY)” NCT06123156 ↗ “Sildenafil, commonly known as Revatio or Viagra, is a medication that increases the supply of blood to the lungs and reduces the workload of the heart.” NCT00763867 ↗ “For example, how often does a man need to take sildenafil (Viagra®) to protect his erectile function or to maximize his erectile function recovery?” NCT00955929 ↗ “The purpose of this study is to assess the safety and efficacy of sildenafil (Viagra) compared with placebo on symptoms during one acute attack.” NCT00145483 ↗ “There are medications, like sildenafil (also known as Viagra), that can help the ability to get back erections in almost 70% of such patients.” NCT00142506 ↗ “Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With Chronic Fatigue Syndrome.” NCT00598585 ↗ “The most commonly used treatment for ED are oral medications like Viagra (sildenafil), Levitra (vardenafil) and Cialis (tadalafil).” NCT00507286 ↗ “Our previous study concluded that one dose of sildenafil (Viagra) lead to an improvement in heart pressure and exercise capacity.” NCT00309790 ↗ “administration of sildenafil (Viagra) in patients with portopulmonary hypertension could be a safe and effective treatment” NCT00145938 ↗ “Vardenafil (Levitra) and Sildenafil (Viagra) are drugs that are marketed for use in patients with erectile dysfunction.” NCT00461565 ↗ “Sildenafil, known as Viagra, is currently used to treat erectile dysfunction and pulmonary hypertension in men.” NCT06237751 ↗ “Sildenafil citrate (trade name: Revatio, Viagra, Respatio, etc.) was emerged as a drug helping vasodilation” NCT06565728 ↗ “The MED includes administration of sildenafil citrate (Viagra) and/or vacuum constriction devices (pump).” NCT01996852 ↗ “The purpose of this study is to study if sildenafil (Viagra) is effective in improving neuropathic pain.” NCT00194909 ↗ “Sildenafil (Viagra) has been well studied and used extensively in males to treat erectile dysfunction.” NCT04565925 ↗ “The purpose of this study is to determine if sildenafil (Viagra) improves exercise tolerance.” NCT00309816 ↗ “Sildenafil Citrate (Viagra®), a vasodilator, is also described as an anti-inflammatory agent.” NCT03766594 ↗ “Pfizer's "Viagra® (sildenafil)" Film Coated Tablet (FCT) formulation (reference formulation)” NCT01769638 ↗ “sildenafil (Viagra, a phosphodiesterase inhibitor that potentates cGMP dependent signaling)” NCT00056433 ↗ “Sildenafil citrate (Viagra) enhances vasodilatation in fetal growth restriction.” PMID 15713717 ↗ Feb 2005 “sildenafil citrate 100 mg film-coated tablet (Viagra®), single dose” NCT00904748 ↗ “Sildenafil (Viagra) is known to reduce pulmonary hypertension.” NCT00781508 ↗ “sildenafil citrate therapy (Viagra®) as 25 mg 3 times daily” NCT02372487 ↗ “Sildenafil citrate (Viagra,pfizer,United states)” NCT04283435 ↗ “Viagra (Sildenafil Citrate) 100 mg” NCT00143260 ↗ “Viagra (Sildenafil Citrate) 100 mg” NCT00137072 ↗ “Sildenafil citrate (Viagra)” NCT00165295 ↗ “Viagra (Sildenafil citrate)” NCT00159809 ↗ “Viagra (Sildenafil citrate)” NCT00301262 ↗ “Viagra (Sildenafil)” NCT00937144 ↗ “Sildenafil (Viagra)” NCT00452582 ↗ “sildenafil (viagra)” NCT00313898 ↗ |
| Known as | Viagra(R) | “Sildenafil (Viagra(R))is widely used by men with Parkinsons Disease (PD) and erectile dysfunction.” NCT01941732 ↗ |
| Action | Inhibit | “sildenafil (Viagra, a phosphodiesterase inhibitor that potentates cGMP dependent signaling)” NCT00056433 ↗ |
| Route | Oral | “oral L-arginine (the substrate for NO synthase) and sildenafil (Viagra, a phosphodiesterase inhibitor that potentates cGMP dependent signaling) will be added” NCT00056433 ↗ |
| Target | CYP3A4 | “sildenafil a CYP3A4 substrate and inhibitor” NCT04170790 ↗ |