Acute Effects of Sildenafil on Endothelial Function in People With Diabetes

Summary

This is a double-blind, placebo-controlled, cross-over trial using a single dose of 100 mg sildenafil or placebo in 40 subjects with T2DM without known cardiovascular disease. Effects on haemodynamic parameters, flow mediated dilatation (FMD) in brachial artery, cardiovascular autonomic function tests, and spontaneous baroreflex sensitivity (BRS) were investigated.

Timeline

Start

2001-08

Primary completion

—

Completion

2003-06

Drugs

Indications