drugset / Trial / NCT00165295
Sildenafil Citrate in Waldenstrom's Macroglobulinemia
Phase 2
Completed
30 enrolled
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the effects (good or bad) that sildenafil (Viagra) has on patients with slow growing Waldenstrom's macroglobulinemia (WM). Sildenafil blocks the function of several proteins necessary to the survival of certain types of cancer and laboratory tests have shown that it can destroy WM cells.
Timeline
- Start
- 2005-09
- Primary completion
- 2007-06
- Completion
- 2007-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sildenafil | Unknown | — | Oral |