drugset / Trial / NCT01481350
Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac Surgery
NaSingle-groupOpen-labelTreatment
Summary
Pulmonary hypertension increases the perioperative risk in patients undergoing cardiac surgery for valvular heart diseases, especially in patients with a long life mitral valve disease. The present study wants to test the hypothesis that intravenous administration of sildenafil reduces pulmonary vascular resistances and afterload of the right ventricle.
Timeline
- Start
- 2012-02
- Primary completion
- 2013-06
- Completion
- 2013-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sildenafil | Unknown | 10 mg | Intravenous |