drugset / Trial / NCT01481350

Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac Surgery

NCT01481350

Phase 2 Completed 20 enrolled University of Turin, Italy
NaSingle-groupOpen-labelTreatment

Summary

Pulmonary hypertension increases the perioperative risk in patients undergoing cardiac surgery for valvular heart diseases, especially in patients with a long life mitral valve disease. The present study wants to test the hypothesis that intravenous administration of sildenafil reduces pulmonary vascular resistances and afterload of the right ventricle.

Timeline

Start
2012-02
Primary completion
2013-06
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Sildenafil Unknown 10 mg Intravenous