drugset / Trial / NCT01499498

The Boceprevir and Sildenafil Pharmacokinetics Study

NCT01499498

Phase 1 Completed 13 enrolled Imperial College London
NaSingle-groupOpen-labelTreatment

Summary

This is a healthy volunteer study looking at the interactions between two drugs: boceprevir and sildenafil. New drugs are being developed to treat people with the chronic viral infection hepatitis C. Very little is know how these new treatments interact with other medications such as the drugs used to treat erectile dysfunction. The purpose of this study is to look at levels of both a new hepatitis C drug called boceprevir (BOC) and an existing erectile dysfunction drug called sildenafil to see if they affect the blood levels of each other when given separately and together.

Timeline

Start
2012-12
Primary completion
2013-04
Completion
2014-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Boceprevir Small molecule 800 mg
Subject Sildenafil Unknown 25 mg