Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia

Summary

This research is being done to evaluate if the phosphodiesterase type 5 (PDE5) inhibitor sildenafil has an effect on the frequency of recurrent priapism and the quality of life of males with sickle cell disease (SCD).

Timeline

Start

2008-06

Primary completion

2012-11

Completion

2013-12

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Sildenafil vs Placebo Then Sildenafil; p = 1; Fisher Exact NCT00940901 ↗

registry analysis (superiority or other test); Sildenafil vs Placebo Then Sildenafil; p = 0.55; Fisher Exact NCT00940901 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sildenafil	Unknown	50 mg	Oral

Indications