drugset / Trial / NCT03236818
Goal Oriented Strategy to Preserve Ejection Fraction Trial
NaSingle-groupOpen-labelTreatment
Summary
In this prospective long term feasibility study we examine whether a goal oriented therapeutic strategy that is able to preserve right ventricular function will result in improved clinical outcome in patients with pulmonary arterial hypertension. We hypothesize that right ventricular function can only be preserved when early and aggressive medical combination therapy not only reduces pulmonary vascular resistance but also pulmonary pressures.
Timeline
- Start
- 2013-05
- Primary completion
- 2017-09
- Completion
- 2017-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bosentan | Other / unclassified | — | — |
| Subject | Macitentan | Other / unclassified | — | — |
| Subject | Sildenafil | Unknown | — | — |
| Subject | Tadalafil | Small molecule | — | — |