drugset / Trial / NCT00136526

Docetaxel and Diethylstilbestrol in the Treatment of Androgen Independent Prostate Cancer

NCT00136526 ↗

Phase 2 Completed 30 enrolled University of Washington Sanofi · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study is for men who have prostate cancer that has spread outside of the prostate gland and is no longer responding to hormone removal therapy. This study is designed to determine if a new drug combination will help to control the cancer. The medicines being used, docetaxel and diethylstilbestrol (DES), have been given to patients with prostate cancer and each drug has demonstrated activity in prostate cancer, either used alone or in other combinations. The objective of this study is to determine the effect of this drug combination on the prostate cancer and its response to disease progression.

Timeline

Start
2002-12
Primary completion
—
Completion
2007-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Diethylstilbestrol Small molecule 1 mg —
Subject Docetaxel Small molecule 36 mg/m2 —

Indications