Post Burn Pruritus Study in Patients Undergoing Wound Healing

Completed 36 enrolled United States Army Institute of Surgical Research

RandomizedCrossoverTriple-blindTreatment

Summary

The purpose of this study is to see if a drug called ondansetron (Zofran) controls itching from healing burn wounds as well or better than the usual drug used, diphenhydramine (Benadryl).

Timeline

Start: 2005-06
Primary completion: 2006-05
Completion: 2006-05

Publications

Background Matheson JD, Clayton J, Muller MJ. The reduction of itch during burn wound healing. J Burn Care Rehabil. 2001 Jan-Feb;22(1):76-81; discussion 75. doi: 10.1097/00004630-200101000-00017.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Diphenhydramine	Unknown	—	—
Comparator	Ondansetron	Other / unclassified	—	—

Indications

No indication recorded.