drugset / Trial / NCT00146718
Anti-Malarial Drug Resistance in Cameroon
Phase 2/3
Completed
755 enrolled
London School of Hygiene and Tropical Medicine
University of Yaounde · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The project is a three-armed study designed to evaluate the efficacy of amodiaquine(AQ), sulphadoxine-pyrimethamine(SP) and(AQ+SP) in three sites in Cameroon that differ in their baseline characteristics for malaria. In addition, drug resistance will be determined by measurement of blood drug levels,and identification of molecular markers of resistance.
Timeline
- Start
- 2003-08
- Primary completion
- —
- Completion
- 2005-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sulphadoxine/Pyrimethamine | Unknown | 25 mg/kg | — |
| Subject | amodiaquine | Other / unclassified | 10 mg/kg | — |