amodiaquine
Trials 81 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT04080895 | Nov 2022 → Apr 2025 | — | University of Oxford | Terminated | No outcome recorded |
| Phase 1 | NCT04002687 | Apr → Oct 2019 | malaria | Medicines for Malaria Venture | Completed | No outcome recorded |
| Phase 1 | NCT02242799 | Jun 2015 → Sep 2016 | HIV infectious disease, malaria | University of Liverpool | Completed | No outcome recorded |
| Phase 1 | NCT00386503 | Jun → Dec 2006 | malaria | Sanofi | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT02696954 | Nov 2016 → Mar 2019 | — | University of Oxford | Terminated | No outcome recorded |
| Phase 1/2 | NCT01319448 | Sep 2011 → Apr 2013 | malaria, sickle cell disease | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 1/2 | NCT01328990 | Apr → Jul 2011 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 27 trials · 1 met primary | ||||||
| Phase 2 | NCT05550909 | Oct → Dec 2022 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | Mixed |
| Phase 2 | NCT05081089 | Oct → Dec 2021 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 2 | NCT04532931 | Sep 2020 → Aug 2021 | COVID-19 | Shin Poong Pharmaceutical Co. Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT04502342 | Jun → Aug 2020 | COVID-19 | Institute for Research and Development of Medicinal and Food Plants of Guinea | Unknown | No outcome recorded |
| Phase 2 | NCT02831023 | Jul 2016 → Jan 2017 | malaria | University of California, San Francisco | Completed | Met primary |
| Phase 2 | NCT00354380 | Sep → Nov 2006 | malaria | Heidelberg University | Completed | No outcome recorded |
| Phase 2 | NCT00261222 | Sep → Nov 2005 | malaria | Heidelberg University | Completed | No outcome recorded |
| Phase 2/35 trials · 1 met primary | ||||||
| Phase 2/3 | NCT05764746 | May 2023 → Dec 2024 | Plasmodium falciparum malaria | Muhimbili University of Health and Allied Sciences | Completed | No outcome recorded |
| Phase 2/3 | NCT00561899 | Aug 2007 → Feb 2008 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 2/3 | NCT00119132 | Jun 2005 → Dec 2006 | malaria | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| Phase 2/3 | NCT00146783 | Jun 2004 → Feb 2007 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 2/3 | NCT00146718 | Aug 2003 → May 2005 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 321 trials · 9 met primary · 1 missed | ||||||
| Phase 3 | NCT05951595 | Sep 2025 → Jul 2026 overdue | Plasmodium falciparum malaria | University of Oxford | Recruiting | No outcome recorded |
| Phase 3 | NCT06923592 | May 2025 → Apr 2027 expected | Plasmodium falciparum malaria, Plasmodium vivax malaria | London School of Hygiene and Tropical Medicine | Recruiting | No outcome recorded |
| Phase 3 | NCT05946642 | Jul 2023 → May 2024 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 3 | NCT05471544 | Jul 2022 → Dec 2024 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 3 | NCT03923725 | Sep 2020 → Mar 2024 | Plasmodium falciparum malaria | University of Oxford | Completed | No outcome recorded |
| Phase 3 | NCT03355664 | Mar 2018 → Mar 2020 | Plasmodium falciparum malaria | University of Oxford | Completed | Missed primary |
| Phase 3 | NCT01374581 | May 2012 → Jun 2014 | malaria | University of Antwerp | Completed | No outcome recorded |
| Phase 3 | NCT01378286 | Jan 2012 → Jun 2013 | malaria | Sanofi | Completed | Met primary |
| Phase 3 | NCT01449045 | Jul → Dec 2011 | malaria | Cheikh Anta Diop University, Senegal | Completed | Met primary |
| Phase 3 | NCT01845701 | Mar 2010 → Apr 2014 | malaria | University of Yaounde 1 | Completed | Met primary |
| Phase 3 | NCT00393679 | Jul 2007 → Dec 2009 | malaria | Institute of Tropical Medicine, Belgium | Completed | Mixed |
| Phase 3 | NCT00432367 | Feb 2007 → Feb 2009 | anemia, malaria, pregnancy disorder | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| Phase 3 | NCT00316329 | Mar 2006 → ? | Plasmodium falciparum malaria | Sanofi | Completed | Met primary |
| Phase 3 | NCT00142246 | Jan 2005 → Apr 2006 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| Phase 3 | NCT00123552 | Nov 2004 → Jun 2006 | malaria | University of California, San Francisco | Completed | Met primary |
| Phase 3 | NCT00406146 | Oct 2004 → Dec 2006 | malaria | University of Ghana Medical School | Unknown | No outcome recorded |
| Phase 3 | NCT00132548 | Jun → Dec 2004 | malaria | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| Phase 3 | NCT00146731 | Jan 2004 → Sep 2007 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00118807 | Aug 2003 → Feb 2004 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00131703 | Mar 2003 → Mar 2005 | malaria, pregnancy disorder | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| Phase 3 | NCT00158548 | Jun 2001 → Dec 2004 | Plasmodium falciparum malaria, Plasmodium vivax malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 430 trials · 1 met primary · 2 missed | ||||||
| Phase 4 | NCT07322068 | Sep 2026 → Jun 2033 expected | Plasmodium falciparum malaria | Stanford University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06967519 | Dec 2025 → Dec 2027 expected | HIV infectious disease, malaria | Yale University | Recruiting | No outcome recorded |
| Phase 4 | NCT06083688 | Oct 2024 → Jul 2025 overdue | Plasmodium falciparum malaria, anemia | Liverpool School of Tropical Medicine | Active not recruiting | No outcome recorded |
| Phase 4 | NCT06337253 | Mar → May 2024 | Plasmodium falciparum malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 4 | NCT05979896 | Jul → Sep 2023 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 4 | NCT05478954 | Jul → Oct 2022 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 4 | NCT04816461 | Jul 2021 → Jun 2023 | malaria | Institut de Recherche en Sciences de la Sante, Burkina Faso | Completed | No outcome recorded |
| Phase 4 | NCT04829695 | Apr → Dec 2021 | Plasmodium falciparum malaria | University of Yaounde 1 | Unknown | No outcome recorded |
| Phase 4 | NCT04618523 | Oct 2020 → Feb 2022 | malaria | Ministry of Public Health, Democratic Republic of the Congo | Completed | No outcome recorded |
| Phase 4 | NCT04565184 | May 2019 → Nov 2020 | Plasmodium falciparum malaria | University of Yaounde 1 | Completed | No outcome recorded |
| Phase 4 | NCT03773536 | May → Sep 2017 | Plasmodium falciparum malaria | Professor Anders Björkman | Completed | No outcome recorded |
| Phase 4 | NCT02940756 | Mar 2017 → Jan 2018 | malaria | Ministry of Public Health, Democratic Republic of the Congo | Completed | No outcome recorded |
| Phase 4 | NCT01697787 | Oct 2012 → Sep 2014 | Plasmodium falciparum malaria | Centre Muraz | Completed | No outcome recorded |
| Phase 4 | NCT01651416 | Jul → Dec 2012 | anemia, malaria | Centre for Global Health Research, Ghana | Completed | No outcome recorded |
| Phase 4 | NCT01023399 | Nov 2009 → Oct 2013 | malaria | Sanofi | Completed | No outcome recorded |
| Phase 4 | NCT00902811 | Dec 2008 → Oct 2009 | Plasmodium falciparum malaria | Medecins Sans Frontieres, Netherlands | Unknown | No outcome recorded |
| Phase 4 | NCT00712374 | Sep 2008 → Dec 2011 | malaria | London School of Hygiene and Tropical Medicine | Unknown | Missed primary |
| Phase 4 | NCT00699920 | Jun 2008 → Jun 2010 | malaria | Sanofi | Completed | Met primary |
| Phase 4 | NCT00540410 | Sep 2007 → Feb 2009 | Plasmodium falciparum malaria | Sanofi | Completed | No outcome recorded |
| Phase 4 | NCT00465257 | May 2007 → ? | malaria | Karolinska University Hospital | Suspended | No outcome recorded |
| Phase 4 | NCT00425763 | May → Aug 2007 | malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 4 | NCT00550160 | Apr 2007 → May 2008 | malaria | Kwame Nkrumah University of Science and Technology | Completed | No outcome recorded |
| Phase 4 | NCT00376155 | May 2006 → Feb 2007 | malaria | London School of Hygiene and Tropical Medicine | Completed | Missed primary |
| Phase 4 | NCT00238017 | Oct → Dec 2005 | malaria | Charite University, Berlin, Germany | Unknown | No outcome recorded |
| Phase 4 | NCT00445796 | Jun 2005 → ? | malaria | Sanofi | Completed | No outcome recorded |
| Phase 4 | NCT00119145 | Jun 2005 → May 2006 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 4 | NCT00164710 | Apr → Sep 2005 | Plasmodium falciparum malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 4 | NCT00164359 | Apr → Sep 2005 | Plasmodium falciparum malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 4 | NCT00137514 | Mar 2001 → May 2004 | Plasmodium falciparum malaria | Bandim Health Project | Completed | No outcome recorded |
| Phase 4 | NCT01204411 | — | Plasmodium falciparum malaria, protein-energy malnutrition | Epicentre | Withdrawn | No outcome recorded |
| Phase not applicable11 trials · 1 met primary · 1 missed | ||||||
| — | NCT06182176 | May → Nov 2024 | Nematoda infectious disease, malaria, schistosomiasis | London School of Hygiene and Tropical Medicine | Unknown | No outcome recorded |
| — | NCT04301531 | Mar 2020 → Nov 2021 | malaria | Noguchi Memorial Institute for Medical Research | Completed | No outcome recorded |
| — | NCT03035305 | Aug → Nov 2016 | malaria | Alliance for International Medical Action | Completed | No outcome recorded |
| — | NCT01634945 | Apr 2012 → May 2013 | anemia | Swiss Federal Institute of Technology | Completed | Missed primary |
| — | NCT01454752 | Nov 2011 → Feb 2012 | anemia, malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| — | NCT01326754 | Aug 2011 → Jun 2012 | Plasmodium falciparum malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| — | NCT00738946 | Aug → Dec 2008 | malaria | London School of Hygiene and Tropical Medicine | Completed | Met primary |
| — | NCT01567423 | Apr 2008 → Apr 2009 | Plasmodium falciparum malaria | Epicentre | Completed | No outcome recorded |
| — | NCT00157885 | Jul → Dec 2005 | Plasmodium falciparum malaria, Plasmodium vivax malaria | Menzies School of Health Research | Completed | No outcome recorded |
| — | NCT00127998 | Jul 2005 → ? | malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| — | NCT00111163 | Mar 2004 → Mar 2006 | anemia, malaria | Centers for Disease Control and Prevention | Completed | Mixed |
| Comparator or background therapy37 trials | ||||||
| Phase 1/2 | NCT00563914 Comparator | Oct 2007 → Nov 2008 | malaria | Sanofi | Completed | No outcome recorded |
| Phase 2 | NCT01955382 Background | Sep 2013 → Jul 2015 | Plasmodium falciparum malaria | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | Missed primary |
| Phase 2 | NCT01407887 Comparator | Aug 2011 | Plasmodium falciparum malaria | Heidelberg University | Completed | No outcome recorded |
| Phase 2 | NCT00545935 Comparator | Jul → Oct 2007 | malaria | Heidelberg University | Completed | No outcome recorded |
| Phase 2 | NCT00323622 Background | Apr 2005 → May 2007 | malaria | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 2/3 | NCT02453308 Comparator | Aug 2015 → Mar 2018 | Plasmodium falciparum malaria | University of Oxford | Completed | No outcome recorded |
| Phase 2/3 | NCT00941785 Comparator | Jul → Dec 2009 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT06173206 Comparator | Jun → Dec 2024 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT03939104 Comparator | Jun 2021 → Jan 2023 | Plasmodium falciparum malaria | University of Oxford | Completed | No outcome recorded |
| Phase 3 | NCT04319380 Comparator | Apr 2020 → Mar 2022 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT04149106 Comparator | Jul 2019 → Dec 2022 | Plasmodium falciparum malaria | University Clinical Research Center, Mali | Unknown | No outcome recorded |
| Phase 3 | NCT03143218 Comparator | Apr 2017 → Mar 2020 | Plasmodium falciparum malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT02211729 Background | May 2014 → Dec 2017 | malaria, respiratory tract infectious disorder | London School of Hygiene and Tropical Medicine | Completed | Missed primary |
| Phase 3 | NCT01231113 Comparator | Jul 2011 → Dec 2012 | Plasmodium falciparum malaria | Kwame Nkrumah University of Science and Technology | Completed | No outcome recorded |
| Phase 3 | NCT01288820 Comparator | Jan 2011 → Apr 2012 | Plasmodium vivax malaria | University of Oxford | Completed | No outcome recorded |
| Phase 3 | NCT01152931 Comparator | Aug → Nov 2010 | malaria | University of Lagos, Nigeria | Completed | No outcome recorded |
| Phase 3 | NCT00944840 Comparator | Sep 2008 → Jul 2009 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00852371 Comparator | Feb → Jun 2008 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00529620 Comparator | Sep → Dec 2007 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00297882 Comparator | Jul 2006 → Apr 2009 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| Phase 4 | NCT06300970 Comparator | Aug 2022 → Aug 2023 | Plasmodium falciparum malaria | Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 4 | NCT05323721 Comparator | Jun → Nov 2022 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 4 | NCT05343312 Comparator | Mar 2022 → Sep 2023 | Plasmodium falciparum malaria | Manhiça Health Research Centre | Completed | No outcome recorded |
| Phase 4 | NCT05186363 Comparator | Jan → Jun 2022 | malaria | Malaria Consortium | Unknown | No outcome recorded |
| Phase 4 | NCT04370977 Comparator | Mar → Sep 2018 | malaria | Manhiça Health Research Centre | Completed | No outcome recorded |
| Phase 4 | NCT03178643 Comparator | Jan 2018 → Dec 2020 | Plasmodium falciparum malaria | Duke University | Completed | No outcome recorded |
| Phase 4 | NCT02741024 Comparator | Oct 2013 → Dec 2014 | malaria | Medecins Sans Frontieres, Netherlands | Completed | No outcome recorded |
| Phase 4 | NCT02168569 Comparator | Jun 2011 → Jan 2012 | Plasmodium falciparum malaria | Manhiça Health Research Centre | Completed | No outcome recorded |
| Phase 4 | NCT04877626 Comparator | Sep 2008 → Oct 2009 | Plasmodium falciparum malaria | National University of Colombia | Completed | No outcome recorded |
| Phase 4 | NCT00374205 Comparator | Sep 2006 → Oct 2007 | Plasmodium falciparum malaria | Bernhard Nocht Institute for Tropical Medicine | Terminated | No outcome recorded |
| Phase 4 | NCT03768908 Comparator | Jan → Jul 2005 | Plasmodium falciparum malaria | Professor Anders Björkman | Completed | No outcome recorded |
| Phase 4 | NCT03764527 Comparator | Nov 2002 → Feb 2003 | Plasmodium falciparum malaria | Professor Anders Björkman | Completed | No outcome recorded |
| — | NCT05354258 Background | Jun → Nov 2022 | Nematoda infectious disease, malaria, schistosomiasis | London School of Hygiene and Tropical Medicine | Unknown | No outcome recorded |
| — | NCT04238845 Background | Jul 2020 → Jul 2021 | malaria, protein-energy malnutrition | Institut de Recherche en Sciences de la Sante, Burkina Faso | Unknown | No outcome recorded |
| — | NCT01967472 Comparator | Sep → Dec 2013 | malaria | London School of Hygiene and Tropical Medicine | Completed | No outcome recorded |
| — | NCT00460369 Comparator | Apr → Nov 2007 | malaria | Research Institute for Development | Completed | No outcome recorded |
| — | NCT00285662 Comparator | Jun 2006 → May 2010 | anemia, malaria | Papua New Guinea Institute of Medical Research | Completed | No outcome recorded |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 119 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Amodiaquine | “If the enzyme activity is normal and no other contra-indication for treatment are found, the participants will be treated with 14 days of primaquine 0.25mg/kg/day OR 7 days of...” NCT06923592 ↗116“Patients received Cospherunate (50 mg Artésunate/125 mg Amodiaquine) at the rate of 2 tablets orally twice daily for 6 days and Azythromycine 250 mg orally at the rate of 2...” NCT04502342 ↗ “Artesunate-amodiaquine fixed dose combination (FDC) (Artesunate Amodiaquine Winthrop® Sanofi Aventis); Artesunate 25mg/amodiaquine 67.5mg; Artesunate 50mg/amodiaquine 135mg ;...” NCT00902811 ↗ “Following the recommendation of the WHO, Ghana changed its malaria treatment guidelines adopting artesunate and amodiaquine as first line for the treatment of uncomplicated...” NCT04301531 ↗ “Amodiaquine (10 mg/kg over 3 days) and Sulfadoxine Pyrimethamine (25 mg of sulfadoxine + 1.25 mg of pyrimethamine per kg in a single dose) or placebo administered over 3 rounds...” NCT00738946 ↗ “This preventive measures involves administering antimalarial drugs (Amodiaquine-Sulfadoxine-Pyrimethamine) to children aged 6- 59 months on a monthly basis during the high...” NCT04238845 ↗ “We will assess the efficacy of a three day course of amodiaquine plus three days of artesunate (AQ3/AS3) for the treatment of symptomatic, uncomplicated P. falciparum infections.” NCT00425763 ↗ “Artesunate 25mg / amodiaquine 67.5mg: 1 tab/day for 3 days in children 5 to 8.9 kg Artesunate 50mg / amodiaquine 135mg: 1 tab/day for 3 days in children 9 to 17.9 kg” NCT01567423 ↗ “One cycle of SMC consisting of sulphadoxine - pyrimethamine (SP) 500mg/25 mg, and amodiaquine (AQ) 150mg on day 1, and AQ 150mg on days 2 and 3.” NCT04319380 ↗ “Children will receive 500mg sulfadoxine plus 25mg pyrimethamine as one tablet, and 153mg amodiaquine (as hydrochloride) as one tablet on Day 0” NCT06173206 ↗ “Monthly administration of sulfadoxine-pyrimethamine plus amodiaquine, combined with community case management” NCT01449045 ↗ |
| Known as | Amodiaquin | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquina | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquine dihydrochloride dihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquine hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | AMODIAQUINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquine hydrochloride dihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquini hydrochloridum | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Amodiaquinum | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | amodiquina | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04877626 ↗ |
| Known as | Camoquin hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | GNF-Pf-5648 | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | NSC-13453 | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | NSC-755863 | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | SJ000110703 | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | Sunoquine | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Known as | TCMDC-123932 | ChEMBL registry synonym — accepted as the source's own label CHEMBL682 ↗ |
| Modality | Other / unclassified | “Artemisinin-based combination treatment” NCT04618523 ↗ |
| Route | Oral | “25 mg/kg oral AQ over a period of three days” NCT00261222 ↗ |