drugset / Trial / NCT00142246
Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
Phase 3
Completed
6758 enrolled
London School of Hygiene and Tropical Medicine
University of Nairobi · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study seeks to establish whether intermittent preventive treatment (IPT) can reduce malaria among school-going children and its consequent impact on school performance.
Timeline
- Start
- 2005-01
- Primary completion
- 2006-04
- Completion
- 2006-04
Publications
- Background Clarke SE, Brooker S, Jukes MCH, Njagi JK, Khasakhala L, Otido J, Crudder C, McGlone B, Magnussen P & Estambale BBA. (2006). Randomised controlled trial of intermittent preventive treatment in schoolchildren: Impact on malaria, anaemia & school performance [abstract]. American Journal of Tropical Medicine & Hygiene Suppl 75 (5): 123.
- Background Clarke S, Njagi J, Jukes M, Estambale B, Khasakhala L, Ajanga A, Luoba A, Otido J, Ochola S & Magnussen P. (2005). Intermittent preventive treatment in schools: Malaria parasitaemia, anaemia and school performance [abstract]. Acta Tropica, Suppl 95: S133.
- Clarke SE, Jukes MC, Njagi JK, Khasakhala L, Cundill B, Otido J, Crudder C, Estambale BB, Brooker S. Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial. Lancet. 2008 Jul 12;372(9633):127-138. doi: 10.1016/S0140-6736(08)61034-X.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sulfadoxine-pyrimethamine | Small molecule | — | Oral |
| Subject | amodiaquine | Other / unclassified | — | Oral |