Triamcinolone Acetonide as an Adjunctive to VPDT in ARMD.

Phase 2/3 Unknown 120 enrolled Canadian Retinal Trials Group QLT Inc. · collab University of British Columbia · collab Vancouver Hospital · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

A 24 - month Study looking at the the changes in visual acuity of patients receiving PDT therapy in conjunction with intravitreal triamcinolone.

Timeline

Start: 2004-01
Primary completion: —
Completion: 2008-03

Outcome

Missed primary endpoint

paper Combination therapy with VPDT and ITA when compared with VPDT therapy alone resulted in no significant difference in final visual acuity at 1 year. PMID 19748675 ↗

Publications

Maberley D; Canadian Retinal Trials Group. Photodynamic therapy and intravitreal triamcinolone for neovascular age-related macular degeneration: a randomized clinical trial. Ophthalmology. 2009 Nov;116(11):2149-57.e1. doi: 10.1016/j.ophtha.2009.04.032. Epub 2009 Sep 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Triamcinolone Acetonide	Other / unclassified	4 mg	Intravitreal