drugset / Trial / NCT00151034
Trastuzumab (Herceptin), Paclitaxel, Carboplatin and Gemcitabine in Advanced Urothelial Cancer
NaSingle-groupOpen-labelTreatment
Summary
Purpose: The purpose of this study is to evaluate the efficacy and safety of treatment with trastuzumab (Herceptin) along with the three other chemotherapy drugs, paclitaxel, carboplatin and gemcitabine, in patients who have advanced urothelial cancer. This clinical trial will also collect information (alternative therapy, response rates, overall survival) from enrolled patients with HER2 negative tumors who are ineligible to receive study treatment.
Timeline
- Start
- 2000-09
- Primary completion
- 2004-08
- Completion
- 2007-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | 5 unknown | — |
| Subject | Gemcitabine | Small molecule | 800 mg/m2 | — |
| Subject | Paclitaxel | Small molecule | 200 mg/m2 | — |
| Subject | Trastuzumab | Monoclonal antibody | 2 mg/kg | — |