drugset
drugset / Trial / NCT00158236

Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

NCT00158236 ↗

Completed 7 enrolled National Institute on Drug Abuse (NIDA)
RandomizedCrossoverDouble-blindTreatment

Summary

Buprenorphine is a medication used to treat opioid addiction, but individuals who use this drug are at risk of abusing it. A buprenorphine and naloxone combination may reduce the likelihood of buprenorphine addiction. This study will evaluate the potential for abuse of buprenorphine and a buprenorphine and naloxone combination in non-dependent opioid users.

Timeline

Start
1997-01
Primary completion
—
Completion
1998-03

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Buprenorphine Other / unclassified 1 mg Other
Subject Buprenorphine Other / unclassified 2 mg Other
Subject Buprenorphine Other / unclassified 4 mg Other
Subject Buprenorphine Other / unclassified 8 mg Other
Subject Buprenorphine Other / unclassified 16 mg Other
Subject Hydromorphone Other / unclassified 2 mg Intramuscular
Subject Hydromorphone Other / unclassified 4 mg Intramuscular
Subject Naloxone Small molecule 0.25 mg Other
Subject Naloxone Small molecule 0.5 mg Other
Subject Naloxone Small molecule 1 mg Other
Subject Naloxone Small molecule 2 mg Other
Subject Naloxone Small molecule 4 mg Other

Indications

opioid abuse