drugset / Trial / NCT00166842

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

NCT00166842

Phase 4 Unknown 40 enrolled National Taiwan University Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to understand the pharmacokinetics of sirolimus tablets in different regimens in newly renal transplant patients, and the effect of dosage form conversion on the concentration of sirolimus in stable renal transplant patients. So that we can design a better tacrolimus or cyclosporine/sirolimus/steroid dose regimen for Taiwanese.

Timeline

Start
2002-09
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Sirolimus Small molecule 0.03 mg/kg Oral
Background Cyclosporine Peptide
Background Tacrolimus Small molecule