drugset / Trial / NCT00168649

Summary

Vitamin A given as treatment and pre-treatment has reduced the severity of symptoms after infusion with endotoxin in several animal models. We intend to examine the effect of vitamin A as pre-treatment on the response to endotoxin in humans. We furthermore wish to examine the long-term effects of vitamin A on the response to endotoxin. We hypothesise that vitamin A decreases endotoxin levels and TNF-alfa responses.

Timeline

Start
2005-06
Primary completion
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Vitamin A Unknown

Indications

No indication recorded.