drugset

drugset / Trial / NCT00169091

Clozapine Versus Haloperidol for Treating the First Episode of Schizophrenia

NCT00169091 ↗

Phase 4 Terminated 32 enrolled Harvard Medical School (HMS and HSDM) Commonwealth Research Center, Massachusetts · collab Dartmouth-Hitchcock Medical Center · collab National Institute of Mental Health (NIMH) · collab Novartis · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will examine the physical responses brought on by clozapine and haloperidol in people experiencing their first episode of schizophrenia.

Timeline

Start: 1996-03
Primary completion: 2003-09
Completion: 2003-10

Publications

Background Green AI, Schildkraut JJ. Should clozapine be a first-line treatment for schizophrenia? The rationale for a double-blind clinical trial in first-episode patients. Harv Rev Psychiatry. 1995 May-Jun;3(1):1-9. doi: 10.3109/10673229509017159.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clozapine	Other / unclassified	300 mg	Oral
Comparator	Haloperidol	Other / unclassified	12 mg	Oral

Indications