Everolimus in Combination With Cyclosporine Microemulsion in de Novo Renal Transplant Recipients

Phase 4 Completed Novartis

RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of the study in de novo renal transplant patients is to evaluate the effect on renal function of an optimized new regimen in comparison with the standard everolimus exposure plus a low-dose cyclosporine microemulsion regimen.

Timeline

Start: 2005-05
Primary completion: 2007-07
Completion: 2007-07

Publications

Results Ponticelli C, Salvadori M, Scolari MP, Citterio F, Rigotti P, Veneziano A, Bartezaghi M; EVEREST Study. Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study. Transplantation. 2011 May 27;91(10):e72-3. doi: 10.1097/TP.0b013e318216c1db. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Everolimus	Small molecule	—	—

Indications

No indication recorded.