Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis

Summary

This study will test the efficacy and safety of topical diclofenac sodium gel in the treatment of hand osteoarthritis.

Timeline

Start

2005-05

Primary completion

—

Completion

2005-12

Outcome

Met primary endpoint

paper At Week 6, diclofenac sodium gel treatment significantly improved each primary outcome measure compared with vehicle. PMID 19648310 ↗

Publications

• Barthel HR, Peniston JH, Clark MB, Gold MS, Altman RD. Correlation of pain relief with physical function in hand osteoarthritis: randomized controlled trial post hoc analysis. Arthritis Res Ther. 2010;12(1):R7. doi: 10.1186/ar2906. Epub 2010 Jan 11.
• Altman RD, Dreiser RL, Fisher CL, Chase WF, Dreher DS, Zacher J. Diclofenac sodium gel in patients with primary hand osteoarthritis: a randomized, double-blind, placebo-controlled trial. J Rheumatol. 2009 Sep;36(9):1991-9. doi: 10.3899/jrheum.081316. Epub 2009 Jul 31.

Drugs

Indications