drugset / Trial / NCT00175123
Effect of Botulinum Toxin in Neurogenic Bladders in Children With Myelomeningocele
Non-randomizedSingle-groupOpen-labelPrevention
Summary
The purpose of this study is to examine how injection of botulinum toxin in the bladder affects bladder function. The trial is carried out in children born with malformation of the spinal cord and subsequent overactive bladders. The purpose of treating the bladder (with different drugs) is to prevent damage to the kidneys and renal function. The aim of this study is to compare a conventionally used drug (oxybutynin) with botulinum toxin. The hypothesis of the study is that botulinum toxin is equal to oxybutynin in the treatment of overactive bladder.
Timeline
- Start
- 2005-05
- Primary completion
- 2008-03
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 12 iu/kg | Other |