drugset

drugset / Trial / NCT00183469

Maintenance Treatment of Bipolar Depression

NCT00183469 ↗

Phase 4 Completed 86 enrolled The University of Texas Health Science Center at San Antonio National Institute of Mental Health (NIMH) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will compare two different antidepressant treatment regimens to determine which is more effective in reducing symptoms of bipolar depression.

Timeline

Start: 2004-12
Primary completion: 2009-02
Completion: 2009-04

Publications

Results Bowden CL, Singh V, Weisler R, Thompson P, Chang X, Quinones M, Mintz J. Lamotrigine vs. lamotrigine plus divalproex in randomized, placebo-controlled maintenance treatment for bipolar depression. Acta Psychiatr Scand. 2012 Nov;126(5):342-50. doi: 10.1111/j.1600-0447.2012.01890.x. Epub 2012 Jun 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Divalproex Sodium	Small molecule	—	—
Comparator	Lamotrigine	Small molecule	—	—

Indications