drugset / Trial / NCT00191672

A Trial Of Gemcitabine Plus Paclitaxel And Gemcitabine Plus Docetaxel In Metastatic Breast Cancer

NCT00191672 ↗

Phase 2 Completed 120 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelTreatment

Summary

The combination of docetaxel and gemcitabine has shown significant activity in patients with metastatic breast cancer. Several studies have activity in patients of multiple lines of therapy, including patients that have been treated with prior taxane therapy. Overall responses have ranged from 30% to 79%. The major side effects of the combination chemotherapy have been neutropenia, anemia, asthenia, neuropathy, nausea, mucositis, and neutropenic fever

Timeline

Start
2003-12
Primary completion
—
Completion
2006-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule — —
Subject Gemcitabine Small molecule — —
Subject Paclitaxel Small molecule — —

Indications