Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder

Summary

The primary objective is to evaluate the safety and efficacy of divalproex extended release (ER) compared to risperidone in the treatment of bipolar disorder with comorbid substance use disorder

Timeline

Start

2004-01

Primary completion

—

Completion

2007-02

Publications

• Background Le Fauve CE, Litten RZ, Randall CL, Moak DH, Salloum IM, Green AI. Pharmacological treatment of alcohol abuse/dependence with psychiatric comorbidity. Alcohol Clin Exp Res. 2004 Feb;28(2):302-12. doi: 10.1097/01.alc.0000113413.37910.d7.

Drugs

Indications