drugset / Trial / NCT00205322

Oxaliplatin, 5-FU and Leucovorin in Combination With Oral Capecitabine for Metastatic Colorectal Cancer

NCT00205322 ↗

Phase 2 Completed 45 enrolled University of Wisconsin, Madison
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The combination of oxaliplatin, 5-FU, leucovorin, and capecitabine is hypothesized to retain and potentially improve upon the activity of the FOLFOX regimens. Additionally, the use of an oral rather than an infusional 5-fu regimen represents a clear advantage in terms of both patient convenience and lack of associated catheter-related complications.

Timeline

Start
2004-04
Primary completion
2007-10
Completion
2007-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule — —
Subject Leucovorin Small molecule — —
Subject Oxaliplatin Small molecule — —
Subject fluorouracil Small molecule — —

Indications