drugset / Trial / NCT00206986
Will Decreased Noradrenergic Activity Normalize Information Processing in Patients With Schizophrenia?
Completed
40 enrolled
Birte Glenthoj
Glostrup University Hospital, Copenhagen · collabLundbeck Foundation · collabUniversity of Copenhagen · collab
RandomizedCrossoverTriple-blindTreatment
Summary
The investigators want to try to improve information processing in schizophrenic patients via pharmacological intervention. The hypothesis is that decreased noradrenergic activity will normalize information processing (PPI, P50 gating, P300, and mismatch negativity) in patients with schizophrenia.
Timeline
- Start
- 2005-05
- Primary completion
- 2011-12
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clonidine | Other / unclassified | 25 ug | — |
| Subject | Clonidine | Other / unclassified | 50 ug | — |
| Subject | Clonidine | Other / unclassified | 75 ug | — |
| Subject | Clonidine | Other / unclassified | 150 ug | — |