drugset / Trial / NCT00209495

Effect of Paracetamol,Pregabalin and Dexamethasone on Pain and Opioid Requirements in Postoperative Patients

NCT00209495

Phase 4 Completed 130 enrolled Glostrup University Hospital, Copenhagen
RandomizedParallel-groupQuadruple-blind

Summary

Women scheduled for abdominal hysterectomy needs postoperative pain treatment, i.e. morphine. Unfortunately morphine has side-effect: nausea, vomiting, sedation and dizziness, which is unpleasant for the patients and sometimes keeps them at bed longer time than needed. We investigate in new combinations of analgesics for postoperative pain, hoping to minimize the need for morphine.

Timeline

Start
2005-06
Primary completion
2007-11
Completion
2008-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 8 mg
Subject Pregabalin Small molecule 300 mg

Indications