Single Dose Versus Multiple Doses of Dexamethasone in Children With Acute Bronchiolitis

Phase 3 Completed 120 enrolled The Hospital for Sick Children The Physicians' Services Incorporated Foundation · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

This study is to determine the effectiveness of five-day treatment versus a single dose of oral dexamethasone (corticosteroid) in children between 2 and 24 months of age with a first episode of acute bronchiolitis presenting in the Emergency Department

Timeline

Start: 2001-12
Primary completion: 2006-04
Completion: 2006-04

Publications

Results Schuh S, Coates AL, Dick P, Stephens D, Lalani A, Nicota E, Mokanski M, Khaikin S, Allen U. A single versus multiple doses of dexamethasone in infants wheezing for the first time. Pediatr Pulmonol. 2008 Sep;43(9):844-50. doi: 10.1002/ppul.20845.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexamethasone	Small molecule	0.15 mg/kg	Oral
Subject	Dexamethasone	Small molecule	1 mg/kg	Oral

Single Dose Versus Multiple Doses of Dexamethasone in Children With Acute Bronchiolitis

Summary

Timeline

Publications

Drugs

Indications