drugset / Trial / NCT00219284

Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease

NCT00219284

Phase 4 Completed 359 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupOpen-labelTreatment

Summary

To assess motor function and quality of life (QoL) in Parkinson's disease (PD) subjects with end-of-dose wearing off, comparing immediate and delayed switch to carbidopa/levodopa and entacapone.

Timeline

Start
2005-01
Primary completion
2008-07
Completion
2008-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Entacapone Small molecule 200 mg
Background Carbidopa Unknown 12.5 mg
Background Carbidopa Unknown 25 mg
Background Carbidopa Unknown 37.5 mg
Background Levodopa Small molecule 50 mg
Background Levodopa Small molecule 100 mg
Background Levodopa Small molecule 150 mg

Indications