Topiramate to Reduce Cocaine Dependence

Summary

Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Topiramate, a medication which lowers dopamine levels, may have the ability to diminish cocaine cravings in addicts. The purpose of this study is to determine the effectiveness of topiramate in reducing cocaine's rewarding effects in individuals addicted to cocaine.

Timeline

Start

2007-01

Primary completion

2010-03

Completion

2010-12

Drugs

Indications