drugset

drugset / Trial / NCT00227942

Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia

NCT00227942 ↗

Phase 4 Completed 86 enrolled Hadine Joffe, MD National Institute of Mental Health (NIMH) · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.

Timeline

Start: 2003-08
Primary completion: —
Completion: 2007-11

Publications

Galvan T, Camuso J, Sullivan K, Kim S, White D, Redline S, Joffe H. Association of estradiol with sleep apnea in depressed perimenopausal and postmenopausal women: a preliminary study. Menopause. 2017 Jan;24(1):112-117. doi: 10.1097/GME.0000000000000737.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Estradiol	Other / unclassified	0.05 mg	Other
Subject	Zolpidem	Small molecule	10 mg	Oral

Indications