drugset / Trial / NCT00228813

G-CSF PMRD: Granulocyte Colony Stimulating Factor (G-CSF) Stimulated Bone Marrow and In Vivo T-Cell Depletion in Patients With Hematologic Malignancies or Bone Marrow Failure Syndrome

NCT00228813

Terminated 8 enrolled Emory University
NaSingle-groupOpen-labelTreatment

Summary

The purposes of this study are: * To examine the engraftment rate in patients receiving in vivo T-cell-depleted G-CSF stimulated bone marrow from partially mismatched related donors. * To evaluate the incidence and severity of acute and chronic graft-versus-host disease in patients receiving in vivo T-cell-depleted G-CSF stimulated bone marrow from partially mismatched related donors.

Timeline

Start
2004-04
Primary completion
2015-01
Completion
2015-01

Drugs

EvaluationDrugModalityDoseRoute
Background filgrastim Protein / enzyme biologic 5 ug/kg Intravenous
Background sargramostim Protein / enzyme biologic 250 ug/m2 Intravenous