Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function

Summary

Bowel function after bowel surgery is delayed (postoperative ileus)by both opiates and the surgery itself. We hypothesized that decreasing opiate use by other analgesics will speed the return of bowel function after surgery. Lidocaine and Ketamine are drugs that appear to be synergistic and do not slow peristalsis. This study is a Randomised Controlled Trial of Lidocaine Infusion Plus Ketamine Injection versus Placebo to to determine whether they will decrease opiate use and then whether decreased opiate use will speed the return of bowel function.

Timeline

Start

2005-09

Primary completion

—

Completion

2006-11

Outcome

Outcome not reported

Stopped: “insufficient numbers of eligible patients as laparscopic surgery increased and open surgery decreased.”

Drugs

Indications