Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity

Summary

The aim of this clinical study is to investigate the efficacy and safety of Dysport® in patients with early onset of upper limb spasticity within 2-12 weeks after stroke.

Timeline

Start

2003-02

Primary completion

—

Completion

2007-10

Outcome

Met primary endpoint

paper At 4 weeks postinjection, BoNT-A significantly improved MAS scores. PMID 22371239 ↗

Publications

• Results Rosales RL, Kong KH, Goh KJ, Kumthornthip W, Mok VC, Delgado-De Los Santos MM, Chua KS, Abdullah SJ, Zakine B, Maisonobe P, Magis A, Wong KS. Botulinum toxin injection for hypertonicity of the upper extremity within 12 weeks after stroke: a randomized controlled trial. Neurorehabil Neural Repair. 2012 Sep;26(7):812-21. doi: 10.1177/1545968311430824. Epub 2012 Feb 27.

Drugs

Indications